Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875738 | 0.80 | MAPT (0.43) | MAPTALDH1A1LMNAKMT2ACSF1R | |
| SCHEMBL17254424 | 0.80 | MAPT (0.43) | MAPTALDH1A1LMNAKMT2ACSF1R | |
| SCHEMBL17254425 | 0.80 | MAPT (0.43) | MAPTALDH1A1LMNAKMT2ACSF1R | |
| SCHEMBL18259557 | 0.78 | MAPT (0.37) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL18259556 | 0.78 | MAPT (0.37) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL18272263 | 0.75 | EIF2AK4 (0.47) | PIM2PIM1 | |
| SCHEMBL16515822 | 0.73 | PIM2 (0.40) | MAPTALDH1A1KDM4EPIM2GAA | |
| SCHEMBL16515825 | 0.73 | PIM2 (0.40) | MAPTALDH1A1KDM4EPIM2GAA | |
| SCHEMBL22289696 | 0.71 | PBK (0.38) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL28625381 | 0.71 | PBK (0.38) | MAPTALDH1A1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016196244-A1 | PYRIDINEAMINE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION (US) | 2016-12-08 | — | — | WO | disclosed |