Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24786607 | 0.83 | SCN9A (0.36) | ARPGRNR3C1NR3C2POLB | |
| SCHEMBL18284619 | 0.78 | AR (0.38) | ARPGRSCN9ATSHR | |
| SCHEMBL18284583 | 0.78 | HTR2A (0.38) | NR3C1SMN1; SMN2HTR2AALDH1A1 | |
| SCHEMBL29551260 | 0.78 | CYP1A2 (0.37) | ARSMN1; SMN2SCN9ACNR2 | |
| SCHEMBL18284593 | 0.78 | CYP1A2 (0.37) | ARSMN1; SMN2SCN9ACNR2 | |
| SCHEMBL22978912 | 0.76 | AR (0.41) | ARPGRNR3C1NR3C2POLB | |
| SCHEMBL29513499 | 0.76 | AR (0.41) | ARPGRNR3C1NR3C2POLB | |
| SCHEMBL23235876 | 0.74 | HTR2A (0.43) | ARSMN1; SMN2POLBGAAHTR2A | |
| SCHEMBL16884618 | 0.74 | POLB (0.46) | ARSMN1; SMN2POLBGAAHTR2A | |
| SCHEMBL9867349 | 0.73 | CA12 (0.41) | SMN1; SMN2HTR2ASCN9AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943486-A1 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | FMC Corporation (US) | 2022-01-26 | — | — | EP | disclosed |
| US-20210300879-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2021-09-30 | — | — | US | disclosed |
| US-11053204-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION (US) | 2021-07-06 | — | — | US | disclosed |
| US-20180105501-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2018-04-19 | — | — | US | disclosed |
| EP-3303305-A1 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016196606-A1 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2016-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105501-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, CBR3, CYP1B1 | AR 2785/4885PGR 964/4885NR3C1 1195/4885 |
| US-11053204-B2 | Pyrimidinyloxy benzene derivatives as herbicides | DDT, CBR3, CYP1B1 | AR 2785/4885PGR 964/4885NR3C1 1195/4885 |
| US-20210300879-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, CBR3, CYP1B1 | AR 2785/4885PGR 964/4885NR3C1 1195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.