Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | GNRHR | P30968 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2655872 | 0.77 | POLB (0.50) | ALDH1A1SMN1; SMN2POLBGAAAR | |
| SCHEMBL16884618 | 0.76 | POLB (0.46) | HTR2ATSHRALDH1A1SMN1; SMN2POLB | |
| SCHEMBL29779908 | 0.74 | POLB (0.45) | HTR2ATSHRALDH1A1SMN1; SMN2POLB | |
| SCHEMBL23860831 | 0.74 | POLB (0.45) | HTR2ATSHRALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11362823 | 0.74 | POLB (0.45) | HTR2ATSHRALDH1A1SMN1; SMN2POLB | |
| SCHEMBL18284622 | 0.74 | AR (0.42) | HTR2ATSHRALDH1A1SMN1; SMN2POLB | |
| SCHEMBL23235818 | 0.73 | AR (0.45) | HTR2ATSHRALDH1A1HTR2CAR | |
| SCHEMBL14181652 | 0.71 | MC4R (0.47) | HTR2A | |
| SCHEMBL4982274 | 0.71 | ALDH1A1 (0.44) | HTR2ATSHRALDH1A1SMN1; SMN2POLB | |
| SCHEMBL9404617 | 0.70 | POLB (0.50) | HTR2ATSHRALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3806836-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | Georgia State University Research Foundation, Inc. (US) | 2021-04-21 | — | — | EP | disclosed |