Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23247716 | 0.81 | KDR (0.36) | MAPTL3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL29808506 | 0.81 | KDR (0.36) | MAPTL3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL27713870 | 0.79 | ALOX5 (0.46) | HTR2AHTR2CMAPTL3MBTL1HPGD | |
| SCHEMBL18284622 | 0.78 | AR (0.42) | HTR2ASMN1; SMN2NR3C1ALDH1A1 | |
| SCHEMBL9046813 | 0.78 | HTR2A (0.41) | HTR2AHTR2CMAPTL3MBTL1HPGD | |
| SCHEMBL9867349 | 0.77 | CA12 (0.41) | HTR2AHTR2CMAPTHPGDLMNA | |
| SCHEMBL23247531 | 0.76 | CYSLTR2 (0.32) | — | |
| SCHEMBL22691166 | 0.76 | L3MBTL1 (0.39) | L3MBTL1CYP1A2CYP2C19KMT2ACYP2D6 | |
| SCHEMBL29551489 | 0.76 | L3MBTL1 (0.39) | L3MBTL1CYP1A2CYP2C19KMT2ACYP2D6 | |
| SCHEMBL149431 | 0.74 | TAAR1 (0.52) | HTR2AHTR2CMAPK1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303305-A1 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016196606-A1 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2016-12-08 | — | — | WO | disclosed |