Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.62 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | PAM | P19021 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2829466 | 0.89 | DGKA (0.61) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL22400778 | 0.89 | DGKA (0.51) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL29164107 | 0.88 | DGKA (0.44) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL4268446 | 0.88 | DGKA (0.59) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL996732 | 0.87 | DGKA (0.67) | DGKADNM1PAMPRSS1PRSS2 | |
| Ethylene Glycol Dihexanoate SCHEMBL435208 | 0.80 | DGKA (0.95) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL28955105 | 0.80 | CYP1A2 (0.47) | DGKATSHRALDH1A1KMT2A | |
| SCHEMBL28429153 | 0.79 | DGKA (0.77) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL18285271 | 0.79 | DGKA (0.77) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL1197282 | 0.78 | DGKA (1.00) | DGKADNM1PAMPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303436-B1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES CO (US) | 2020-12-09 | — | — | EP | disclosed |
| US-10266472-B2 | Hydrofluoroolefins and methods of using same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-04-23 | — | — | US | disclosed |
| US-20180141887-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-24 | — | — | US | disclosed |
| EP-3303436-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M Innovative Properties Company (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016196242-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266472-B2 | Hydrofluoroolefins and methods of using same | RFT1, AFF1, RFC3 | DGKA 3922/4885DNM1 2147/4885PAM 3375/4885 |
| US-20180141887-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | RFT1, AFF1, RFC3 | DGKA 3922/4885DNM1 2147/4885PAM 3375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.