Sugi Predict
/ Targets
/ RFC3
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
Clinical trials — most relevant to RFC3 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
| Management of Retinitis Pigmentosa Via Combination of Wharton's Jelly-derived Mesenchymal Stem Cells and Magnovision |
PHASE3 | COMPLETED |
| Veliparib With or Without Radiation Therapy, Carboplatin, and Paclitaxel in Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery |
PHASE1/PHASE2 | ACTIVE_NOT_RECRUITING |
| Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers |
PHASE1/PHASE2 | COMPLETED |
| Genetic Changes in Patients With Non-Small Cell Lung Cancer Who Are Receiving Vinorelbine and Gemcitabine Before Surgery |
PHASE2 | COMPLETED |
| A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies |
PHASE1/PHASE2 | RECRUITING |
| I/II Phase Study Evaluating M1774 in Combination With Fulvestrant in HR+ and HER2- Advanced Breast Cancers |
PHASE1/PHASE2 | NOT_YET_RECRUITING |
| S0720: Adjuvant Therapy Based on Gene Expression in Stage IA and IB Non-Small Cell Lung Cancer |
PHASE2 | COMPLETED |
| A Phase I Trial of SHR3162 in Subjects With Advanced Solid Tumors |
PHASE1 | COMPLETED |
| Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors |
PHASE1 | COMPLETED |
| Chronic Cough and CANVAS (Cerebellar Ataxia With Neuropathy and Bilateral Vestibular Areflexia Syndrome) |
nan | COMPLETED |
| Spironolactone and XPB-1 Integrity in the TFIIH Complex |
nan | ENROLLING_BY_INVITATION |
| Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS |
nan | RECRUITING |
| Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics |
nan | UNKNOWN |
| Assessing Colonic Folate Absorption & Metabolism |
nan | UNKNOWN |
| Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases |
nan | UNKNOWN |
| Sodium Transport: Genetics and Hypertension |
nan | COMPLETED |
| Autophagy in Systemic Lupus Erythematosus |
nan | UNKNOWN |
| Genomics of In-Stent Restenosis |
nan | COMPLETED |
| Phenotyping of Small Bowel Adenocarcinoma |
nan | COMPLETED |
| Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients |
nan | ACTIVE_NOT_RECRUITING |
| Studying Tissue Samples From Patients With Stage II Colon Cancer Treated on Clinical Trial CLB-9581 |
nan | COMPLETED |
| Study of Proteins in Head and Neck Cancer Cells |
nan | COMPLETED |
| Biomarkers in Patients With Diffuse Large B-Cell Lymphoma Treated With Combination Chemotherapy With or Without Rituximab |
nan | COMPLETED |
| MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy |
nan | UNKNOWN |
| Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders |
nan | RECRUITING |
| Genetic Basis of Abdominal Aortic Aneurysm |
nan | COMPLETED |
| Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives |
nan | UNKNOWN |
| A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients |
nan | COMPLETED |
| Study of the Effect of Innate on the Inflammatory Response to Endotoxin |
nan | RECRUITING |
| LobularCard Trial: Searching for Novel Germline Mutations in Lobular Breast Cancer Patients |
nan | ACTIVE_NOT_RECRUITING |
Related proteins — ESM-2 sequence neighbours (a RFC3 binder may also engage these)