SCHEMBL1828620

SCHEMBL1828620

OB(O)Oc1cccc(F)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
MAOB P27338 1/20 0.40
ENPP2 Q13822 1/20 0.39
NFE2L2 Q16236 2/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
ESR2 Q92731 2/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
ESR1 P03372 1/20 0.39
HDAC1 Q13547 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
ACHE P22303 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HPGD P15428 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31395446 1.00 PPARG (0.40) PPARGPPARAMAOBENPP2NFE2L2
SCHEMBL28194677 0.98 PPARG (0.39) PPARGPPARAMAOBENPP2NFE2L2
SCHEMBL28090593 0.87 CA1 (0.44) SLC6A2SLC6A4SLC6A3
SCHEMBL29441920 0.87 CA1 (0.44) SLC6A2SLC6A4SLC6A3
SCHEMBL6677730 0.84 ENPP2 (0.41) ENPP2CES2CES1ACHE
SCHEMBL27781798 0.83 VEGFA (0.41) SLC6A2SLC6A4SLC6A3
SCHEMBL2163061 0.82 NFE2L2 (0.41) PPARGPPARAMAOBNFE2L2CES2
SCHEMBL27895043 0.81 FFAR1 (0.45) NPC1RAB9A
SCHEMBL28237167 0.80 PPARG (0.36) PPARGPPARAENPP2NFE2L2CES2
SCHEMBL760689 0.77 CA12 (0.39) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120033221-A Silicon-based composite material, preparation method thereof and secondary battery 兰溪致德新能源材料有限公司 2025-05-23 CN claimed
CN-119174838-A Sugar-responsive multifunctional hydrogel, preparation method thereof and application thereof in wound dressing 武汉大学中南医院 2024-12-24 CN claimed
CN-119137161-A Palladium catalyst for vinyl addition polymer formation with improved film forming properties 普罗米鲁斯有限责任公司 2024-12-13 CN claimed
CN-118772131-A Biaryl compound and preparation method and application thereof 河南大学 2024-10-15 CN claimed
CN-114008106-B Radiation curable composition by anionic polymerization 汉高股份有限及两合公司 2024-08-16 CN claimed
CN-116096760-B Hindered amine stabilized UV-active organopalladium catalyzed polycycloolefin compositions as optical materials 住友电木株式会社 2024-08-02 CN claimed
CN-118336009-A Phenylboronic acid-based additive and electrolyte for lithium/carbon fluoride primary battery 上海大学 2024-07-12 CN claimed
CN-118203703-A Material and method for producing scaffolds for receiving cells 朗格生物技术公共公益股份有限公司 2024-06-18 CN claimed
CN-112703020-B Material and method for producing scaffolds for receiving cells 朗格生物技术公共公益股份有限公司 2024-04-16 CN claimed
CN-116731652-A Single-component yellowing-resistant ultraviolet light delay curing type Mini LED epoxy packaging adhesive and preparation method thereof 信泰永合(烟台)新材料有限公司 2023-09-12 CN claimed
CN-116675877-A Preparation method and application of double-network photonic crystal hydrogel for visual blood glucose detection 武汉大学 2023-09-01 CN claimed
CN-116675876-A Preparation method and application of photonic crystal hydrogel for visual blood glucose detection 武汉大学深圳研究院 2023-09-01 CN claimed
CN-116096760-A Hindered amine stabilized UV-active organopalladium catalyzed polycycloolefin compositions as optical materials 普罗米鲁斯有限责任公司 2023-05-09 CN claimed
CN-114901712-A AsPd (AcAc) of optical Material 2 UV active derivatives of L catalyzed polycycloolefin compositions 普罗米鲁斯有限责任公司 2022-08-12 CN claimed
CN-114901711-A UV-active derivatives of Pd (AcAc) 2-catalyzed polycycloolefin compositions as optical materials 普罗米鲁斯有限责任公司 2022-08-12 CN claimed
EP-1506176-B1 AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PFIZER ITALIA SRL (IT) 2013-04-24 EP claimed
CN-1208360-C In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes SUMITOMO BAKELITE CO (JP) 2005-06-29 CN claimed
JP-11116580-A None JP disclosed
EP-0675118-A2 Biphenylderivatives, process for their preparation and their use as medicaments Eisai Co., Ltd. (JP) 1995-10-04 EP disclosed
EP-0574794-A1 Organic transition metal compound having a pi-bonding heterocyclic ligand and method of polymerizing olefins by using the same TOSOH CORPORATION (JP) 1993-12-22 EP disclosed