Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18436532 | 0.80 | BRD4 (0.40) | BRD4SMN1; SMN2L3MBTL1TSHRHSD17B10 | |
| SCHEMBL13083322 | 0.80 | KAT2B (0.37) | BRD4SMN1; SMN2L3MBTL1TSHRHSD17B10 | |
| SCHEMBL1757958 | 0.79 | L3MBTL1 (0.42) | BRD4SMN1; SMN2L3MBTL1TSHRHSD17B10 | |
| SCHEMBL21904789 | 0.79 | L3MBTL1 (0.42) | BRD4SMN1; SMN2L3MBTL1TSHRHSD17B10 | |
| SCHEMBL18378752 | 0.78 | CYP1A2 (0.46) | BRD4SMN1; SMN2L3MBTL1TSHRHSD17B10 | |
| SCHEMBL25004046 | 0.77 | L3MBTL1 (0.40) | BRD4SMN1; SMN2L3MBTL1TSHRHSD17B10 | |
| SCHEMBL1876668 | 0.76 | SLC6A2 (0.50) | SMN1; SMN2HSD17B10ALDH1A1KDM4EMGAM | |
| SCHEMBL30633715 | 0.74 | GAA (0.48) | SMN1; SMN2HSD17B10PTGDR2ALDH1A1CYP2C19 | |
| SCHEMBL31309060 | 0.74 | SMN1; SMN2 (0.38) | BRD4SMN1; SMN2L3MBTL1TSHRHSD17B10 | |
| SCHEMBL22094637 | 0.74 | SMN1; SMN2 (0.38) | BRD4SMN1; SMN2L3MBTL1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180201627-A9 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-07-19 | — | — | US | disclosed |
| US-20170037062-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-09 | — | — | US | disclosed |
| US-9512147-B2 | Organoboron compounds and methods of making organoboron compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180201627-A9 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | NDC1, ELOC, UGT2B7 | BRD4 1691/4885SMN1; SMN2 1952/4885L3MBTL1 293/4885 |
| US-20170037062-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | NDC1, ELOC, UGT2B7 | BRD4 1691/4885SMN1; SMN2 1952/4885L3MBTL1 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.