Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1801642 | 0.98 | DPP4 (0.30) | DPP4DPP8DPP9 | |
| SCHEMBL890070 | 0.83 | — | — | |
| SCHEMBL14922230 | 0.83 | — | — | |
| SCHEMBL12621128 | 0.80 | SLC18A2 (0.35) | — | |
| SCHEMBL27372552 | 0.79 | OPRM1 (0.32) | — | |
| SCHEMBL9660811 | 0.77 | — | — | |
| SCHEMBL24900947 | 0.77 | — | — | |
| SCHEMBL14440030 | 0.77 | — | — | |
| SCHEMBL14376715 | 0.76 | CASP3 (0.36) | — | |
| SCHEMBL23449320 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315767-B1 | PYRIDINO-PYRIDINONE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2013-09-04 | — | — | EP | disclosed |
| EP-2315767-A2 | PYRIDINO-PYRIDINONE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010004197-A2 | PYRIDINO-PYRIDINONE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-01-14 | — | — | WO | disclosed |