SCHEMBL182879

SCHEMBL182879

CCCn1cc2c(c1)OCCCO2

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.32
DRD2 P14416 1/20 0.31
DRD3 P35462 1/20 0.31
HTR2C P28335 3/20 0.31
HTR1A P08908 2/20 0.31
HTR1D P28221 2/20 0.31
HTR2A P28223 1/20 0.31
KDM2B Q8NHM5 1/20 0.31
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182518 0.85 NPC1 (0.40)
SCHEMBL3250243 0.79 SMN1; SMN2 (0.31)
SCHEMBL3251038 0.79 GRM5 (0.33) PKM
SCHEMBL182476 0.77 KDM4E (0.32)
SCHEMBL182198 0.77 ITGB2 (0.33) PKMHTR2CHTR1AHTR1DHTR2A
SCHEMBL17646200 0.76 NPC1 (0.42)
SCHEMBL17646207 0.76 NPC1 (0.42)
SCHEMBL2372400 0.72 POLB (0.32) DRD2DRD3
SCHEMBL14046558 0.71 CHRM2 (0.40) DRD3HTR1A
SCHEMBL3255129 0.71 CYP3A4 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465962-B1 ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES UNIV FLORIDA (US) 2012-01-04 EP disclosed
US-6791738-B2 CONTROLLING COLOR, BRIGHTNESS AND ENVIRONMENTAL STABILITY; POLY- 3,4-ALKYLENEDIOXYHETEROCYCLES UNIVERSITY OF FLORIDA 2004-09-14 US disclosed
US-20030174377-A1 Electrochromic polymers and polymer electrochromic devices UNIVERSITY OF FLORIDA 2003-09-18 US disclosed