Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2721504 | 0.81 | MEN1 (0.37) | SMN1; SMN2 | |
| SCHEMBL182879 | 0.79 | PKM (0.32) | — | |
| SCHEMBL3251038 | 0.75 | GRM5 (0.33) | ALDH1A1 | |
| SCHEMBL182518 | 0.73 | NPC1 (0.40) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL182198 | 0.72 | ITGB2 (0.33) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL3241096 | 0.72 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL182476 | 0.70 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL3241038 | 0.67 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL17646200 | 0.64 | NPC1 (0.42) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL17646207 | 0.64 | NPC1 (0.42) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799932-B2 | N-substituted 3,4-alkylenedioxypyrroles, ester substituted dihydroxypyrroles and methods for synthesis of these pyrroles | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| US-7799932-B2 | N-substituted 3,4-alkylenedioxypyrroles, ester substituted dihydroxypyrroles and methods for synthesis of these pyrroles | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| US-7799932-B2 | N-substituted 3,4-alkylenedioxypyrroles, ester substituted dihydroxypyrroles and methods for synthesis of these pyrroles | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| EP-1931630-B1 | N-SUBSTITUTED 3,4-ALKYLENEDIOXYPYRROLES, ESTER SUBSTITUTED DIHYDROXYPYRROLES AND METHODS FOR SYNTHESIS OF THESE PYRROLES | UNIV FLORIDA (US) | 2010-05-12 | — | — | EP | disclosed |
| EP-1931630-B1 | N-SUBSTITUTED 3,4-ALKYLENEDIOXYPYRROLES, ESTER SUBSTITUTED DIHYDROXYPYRROLES AND METHODS FOR SYNTHESIS OF THESE PYRROLES | UNIV FLORIDA (US) | 2010-05-12 | — | — | EP | disclosed |
| US-20090149661-A1 | N-Substituted 3,4-Alkylenedioxypyrroles, Ester Substituted Dihydroxypyrroles and Methods for Synthesis of These Pyrroles | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-06-11 | — | — | US | disclosed |
| US-20090149661-A1 | N-Substituted 3,4-Alkylenedioxypyrroles, Ester Substituted Dihydroxypyrroles and Methods for Synthesis of These Pyrroles | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-06-11 | — | — | US | disclosed |
| US-20090149661-A1 | N-Substituted 3,4-Alkylenedioxypyrroles, Ester Substituted Dihydroxypyrroles and Methods for Synthesis of These Pyrroles | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-06-11 | — | — | US | disclosed |
| WO-2007041724-A1 | N-SUBSTITUTED 3,4-ALKYLENEDIOXYPYRROLES, ESTER SUBSTITUTED DIHYDROXYPYRROLES AND METHODS FOR SYNTHESIS OF THESE PYRROLES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149661-A1 | N-Substituted 3,4-Alkylenedioxypyrroles, Ester Substituted Dihydroxypyrroles and Methods for Synthesis of These Pyrroles | PAH, DDT, DHPS | SMN1; SMN2 4448/4885ALDH1A1 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.