SCHEMBL18289073

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15811189	0.77	AHR (0.47)	SMN1; SMN2ALDH1A1AHRKIF11KMT2A
	SCHEMBL15811051	0.77	AHR (0.47)	SMN1; SMN2ALDH1A1AHRKIF11KMT2A
	SCHEMBL19051616	0.76	KDM4E (0.38)	RAB9AALDH1A1POLBAHRKIF11
	SCHEMBL19961720	0.75	RAB9A (0.61)	LRRK2NPC1RAB9ASMN1; SMN2ALDH1A1
	SCHEMBL13052911	0.74	CYP11B2 (0.55)	LRRK2NPC1RAB9ASMN1; SMN2ALDH1A1
	SCHEMBL30353949	0.73	AHR (0.53)	ALDH1A1AHRKIF11KDM4EGPR3
	SCHEMBL16397572	0.73	AHR (0.53)	ALDH1A1AHRKIF11KDM4EGPR3
	SCHEMBL25006958	0.72	AHR (0.44)	ALDH1A1AHRKIF11MEN1KMT2A
	SCHEMBL19780904	0.72	NPC1 (0.61)	LRRK2NPC1RAB9ASMN1; SMN2CYP11B1
	SCHEMBL16397780	0.71	AHR (0.50)	ALDH1A1AHRKIF11KDM4EGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.