Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 4/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | POLA1 | P09884 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 18-Hydroxyferruginol SCHEMBL18290210 | 0.87 | KARS1 (0.67) | KARS1NR1I2OPRK1CYP3A4MEN1 | |
| 18-Hydroxyferruginol SCHEMBL32666150 | 0.87 | KARS1 (0.67) | KARS1NR1I2OPRK1CYP3A4MEN1 | |
| Lambertic Acid SCHEMBL31674429 | 0.84 | NR1I2 (0.74) | KARS1NR1I2OPRK1CYP3A4POLA1 | |
| Ferruginol SCHEMBL155580 | 0.82 | KARS1 (0.73) | KARS1NR1I2OPRK1CYP3A4MEN1 | |
| Ferruginol SCHEMBL13423521 | 0.82 | KARS1 (0.73) | KARS1NR1I2OPRK1CYP3A4MEN1 | |
| Ferruginol SCHEMBL5315022 | 0.82 | KARS1 (0.73) | KARS1NR1I2OPRK1CYP3A4MEN1 | |
| SCHEMBL20856804 | 0.82 | KARS1 (0.76) | KARS1CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL14648824 | 0.78 | NR1I2 (0.50) | KARS1NR1I2OPRK1CYP3A4MEN1 | |
| Sempervirol SCHEMBL10524413 | 0.77 | KARS1 (0.66) | KARS1NR1I2OPRK1CYP3A4MEN1 | |
| Sempervirol SCHEMBL29495146 | 0.77 | KARS1 (0.66) | KARS1NR1I2OPRK1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016192631-A1 | ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME | 中国科学院上海药物研究所 | 2016-12-08 | — | — | WO | disclosed |