Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 2/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 7/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | BCL9 | O00512 | 3/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ferruginol SCHEMBL155580 | 1.00 | KARS1 (0.73) | KARS1CYP19A1USP2CYP3A4MAPT | |
| Ferruginol SCHEMBL13423521 | 1.00 | KARS1 (0.73) | KARS1CYP19A1USP2CYP3A4MAPT | |
| Sempervirol SCHEMBL10524413 | 0.95 | KARS1 (0.66) | KARS1CYP19A1USP2CYP3A4MAPT | |
| Sempervirol SCHEMBL10524412 | 0.95 | KARS1 (0.66) | KARS1CYP19A1USP2CYP3A4MAPT | |
| Sempervirol SCHEMBL29495146 | 0.95 | KARS1 (0.66) | KARS1CYP19A1USP2CYP3A4MAPT | |
| SCHEMBL18290298 | 0.88 | KARS1 (0.58) | KARS1CYP19A1USP2CYP3A4MAPT | |
| 18-Hydroxyferruginol SCHEMBL32666150 | 0.85 | KARS1 (0.67) | KARS1USP2CYP3A4MAPTMEN1 | |
| 18-Hydroxyferruginol SCHEMBL18290210 | 0.85 | KARS1 (0.67) | KARS1USP2CYP3A4MAPTMEN1 | |
| SCHEMBL21444399 | 0.85 | KARS1 (0.57) | KARS1CYP19A1USP2CYP3A4MAPT | |
| Lambertic Acid SCHEMBL31674429 | 0.84 | NR1I2 (0.74) | KARS1CYP3A4NR1I2OPRK1BCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1311018-A | — | — | None | — | — | JP | disclosed |
| US-20130150456-A1 | ANTIBACTERIAL AGENT AND DISINFECTING METHOD | MITSUBISHI-KAGAKU FOODS CORPORATION (JP) | 2013-06-13 | — | — | US | disclosed |
| US-20130150456-A1 | ANTIBACTERIAL AGENT AND DISINFECTING METHOD | MITSUBISHI-KAGAKU FOODS CORPORATION (JP) | 2013-06-13 | — | — | US | disclosed |
| US-20110151034-A1 | ANTIBACTERIAL AGENT AND DISINFECTING METHOD | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |
| US-20110151034-A1 | ANTIBACTERIAL AGENT AND DISINFECTING METHOD | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |
| EP-2316267-A1 | ANTIBACTERIAL AGENT AND DISINFECTING METHOD | Mitsubishi Chemical Corporation (JP) | 2011-05-04 | — | — | EP | disclosed |
| WO-2007038875-A1 | CCR5 RECEPTOR ANTAGONIST MOLECULES | AVANCE PHARMA INC. (CA) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007038875-A1 | CCR5 RECEPTOR ANTAGONIST MOLECULES | AVANCE PHARMA INC. (CA) | 2007-04-12 | — | — | WO | disclosed |
| JP-H01311018-A | ANTIBACTERIAL AGENT FOR GRAM-POSITIVE ANAEROBIC BACTERIUM, EXTERNAL PREPARATION OF SKIN AND COMPOSITION FOR ORAL CAVITY USING THE SAME AGENT | SHISEIDO CO LTD | 1989-12-15 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110151034-A1 | ANTIBACTERIAL AGENT AND DISINFECTING METHOD | LCT, DNASE1, LPO | KARS1 1810/4885CYP19A1 3213/4885USP2 1872/4885 |
| US-20130150456-A1 | ANTIBACTERIAL AGENT AND DISINFECTING METHOD | LCT, DNASE1, LPO | KARS1 1810/4885CYP19A1 3213/4885USP2 1872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.