Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18281279 | 0.88 | CHKA (0.43) | IDEMEN1KMT2ACLK1SMN1; SMN2 | |
| SCHEMBL18281277 | 0.88 | CHKA (0.43) | IDEMEN1KMT2ACLK1SMN1; SMN2 | |
| SCHEMBL6489302 | 0.78 | HSD17B10 (0.41) | IDEMEN1KMT2ACLK1BRD4 | |
| SCHEMBL6489308 | 0.78 | HSD17B10 (0.41) | IDEMEN1KMT2ACLK1BRD4 | |
| SCHEMBL2081892 | 0.74 | SPHK1 (0.41) | MEN1KMT2ABRD4 | |
| SCHEMBL2081890 | 0.74 | SPHK1 (0.41) | MEN1KMT2ABRD4 | |
| SCHEMBL8945093 | 0.72 | FAAH (0.41) | KMT2ABRD4ALDH1A1MAPT | |
| SCHEMBL2080215 | 0.71 | BRD4 (0.40) | BRD4 | |
| SCHEMBL2080211 | 0.71 | BRD4 (0.40) | BRD4 | |
| SCHEMBL1833586 | 0.71 | BRD4 (0.47) | MEN1KMT2ABRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016196393-A2 | AUTOPHAGY-INHIBITING COMPOUNDS AND USES THEREOF | PRESAGE BIOSCIENCES, INC. (US) | 2016-12-08 | — | — | WO | disclosed |