Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945204 | 0.90 | HTR2C (0.38) | BRD4SPHK1SSTR4TP53HSD11B2 | |
| SCHEMBL31752274 | 0.76 | SPHK1 (0.38) | BRD4EPHA2SPHK1HSD11B2 | |
| SCHEMBL3612721 | 0.73 | SPHK1 (0.44) | BRD4SPHK1HSD11B2KMT2A | |
| SCHEMBL19357528 | 0.73 | SPHK1 (0.44) | BRD4SPHK1HSD11B2KMT2A | |
| SCHEMBL3612715 | 0.73 | SPHK1 (0.44) | BRD4SPHK1HSD11B2KMT2A | |
| SCHEMBL18959547 | 0.73 | BRD4 (0.47) | BRD4SPHK1HSD11B2ALDH1A1KMT2A | |
| SCHEMBL15209134 | 0.72 | SPHK1 (0.48) | BRD4SPHK1HSD11B2 | |
| SCHEMBL15209132 | 0.72 | SPHK1 (0.48) | BRD4SPHK1HSD11B2 | |
| SCHEMBL1833586 | 0.72 | BRD4 (0.47) | BRD4SPHK1ALDH1A1KMT2A | |
| SCHEMBL1833587 | 0.72 | BRD4 (0.47) | BRD4SPHK1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |