Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | GLB1 | P16278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290247 | 1.00 | SLC6A3 (0.42) | SLC6A3CA1CA2CA4NOS1 | |
| SCHEMBL22972544 | 0.92 | SLC6A3 (0.39) | SLC6A3CA1CA2CA4NOS1 | |
| SCHEMBL17826725 | 0.85 | SLC6A3 (0.38) | SLC6A3CA1CA2CA4NOS1 | |
| SCHEMBL18723476 | 0.85 | SLC6A3 (0.38) | SLC6A3CA1CA2CA4NOS1 | |
| SCHEMBL18570094 | 0.83 | SLC6A3 (0.37) | SLC6A3CA1CA2CA4NOS1 | |
| SCHEMBL21948713 | 0.83 | SLC6A3 (0.37) | SLC6A3CA1CA2CA4NOS1 | |
| SCHEMBL16002400 | 0.82 | SLC6A3 (0.31) | SLC6A3NOS1NOS2 | |
| SCHEMBL24196773 | 0.81 | SLC6A3 (0.36) | SLC6A3CA1CA2CA4NOS1 | |
| SCHEMBL12750037 | 0.79 | SLC6A3 (0.49) | SLC6A3CA1CA2CA4 | |
| SCHEMBL19368271 | 0.79 | SLC6A3 (0.35) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016196393-A2 | AUTOPHAGY-INHIBITING COMPOUNDS AND USES THEREOF | PRESAGE BIOSCIENCES, INC. (US) | 2016-12-08 | — | — | WO | disclosed |