Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290263 | 0.83 | SLC6A3 (0.42) | SLC6A3NOS1NOS2CA1CA2 | |
| SCHEMBL18290247 | 0.83 | SLC6A3 (0.42) | SLC6A3NOS1NOS2CA1CA2 | |
| SCHEMBL21948714 | 0.81 | — | — | |
| SCHEMBL26465879 | 0.81 | — | — | |
| SCHEMBL16204542 | 0.81 | — | — | |
| SCHEMBL14431964 | 0.81 | — | — | |
| SCHEMBL13906059 | 0.81 | SLC6A3 (0.44) | SLC6A3CA1CA2CA4 | |
| SCHEMBL19984469 | 0.81 | SLC6A3 (0.44) | SLC6A3CA1CA2CA4 | |
| SCHEMBL19984466 | 0.81 | SLC6A3 (0.44) | SLC6A3CA1CA2CA4 | |
| SCHEMBL23890063 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081508-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-04-23 | — | — | WO | disclosed |