Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.66 |
| ▸ | FDPS | P14324 | 10/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.41 |
| ▸ | SOD1 | P00441 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929294 | 1.00 | EP300 (0.66) | EP300FDPSGGPS1SOD1HSP90AA1 | |
| Taxodione SCHEMBL23630260 | 0.80 | EP300 (1.00) | EP300FDPSGGPS1HSP90AA1KDM4E | |
| Taxodione SCHEMBL3847860 | 0.80 | EP300 (1.00) | EP300FDPSGGPS1HSP90AA1KDM4E | |
| SCHEMBL18290366 | 0.71 | EP300 (0.66) | EP300FDPSGGPS1SOD1HSP90AA1 | |
| SCHEMBL16010811 | 0.70 | CYP19A1 (0.37) | EP300FDPSSOD1HSP90AA1KDM4E | |
| SCHEMBL16010808 | 0.70 | CYP19A1 (0.37) | EP300FDPSSOD1HSP90AA1KDM4E | |
| SCHEMBL16011025 | 0.70 | CYP19A1 (0.37) | EP300FDPSSOD1HSP90AA1KDM4E | |
| SCHEMBL18290370 | 0.67 | EP300 (0.51) | EP300FDPSGGPS1MEN1USP2 | |
| SCHEMBL22861899 | 0.66 | EP300 (0.42) | EP300FDPSGGPS1SOD1CYP19A1 | |
| SCHEMBL22861898 | 0.66 | EP300 (0.42) | EP300FDPSGGPS1SOD1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016192631-A1 | ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME | 中国科学院上海药物研究所 | 2016-12-08 | — | — | WO | disclosed |