Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | SOD1 | P00441 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 3/20 | 0.31 |
| ▸ | BCL9 | O00512 | 3/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16010808 | 1.00 | CYP19A1 (0.37) | CYP19A1SOD1CYP3A4USP2MAPT | |
| SCHEMBL16010811 | 1.00 | CYP19A1 (0.37) | CYP19A1SOD1CYP3A4USP2MAPT | |
| SCHEMBL14880080 | 0.77 | TRPA1 (0.34) | CYP19A1SOD1CYP3A4MAPTEP300 | |
| SCHEMBL11451547 | 0.77 | TRPA1 (0.34) | CYP19A1SOD1CYP3A4MAPTEP300 | |
| SCHEMBL14882179 | 0.77 | TRPA1 (0.34) | CYP19A1SOD1CYP3A4MAPTEP300 | |
| SCHEMBL18290373 | 0.70 | EP300 (0.66) | CYP19A1SOD1CYP3A4USP2MAPT | |
| SCHEMBL14879678 | 0.64 | EP300 (0.40) | CYP19A1CYP3A4USP2MAPTTP53 | |
| SCHEMBL14880141 | 0.64 | EP300 (0.40) | CYP19A1CYP3A4USP2MAPTTP53 | |
| SCHEMBL14882079 | 0.63 | EP300 (0.54) | CYP19A1CYP3A4USP2MAPTTP53 | |
| SCHEMBL16010952 | 0.63 | EP300 (0.54) | CYP19A1CYP3A4USP2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768307-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| US-20170137398-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2017-05-18 | — | — | US | disclosed |
| US-9499464-B2 | Opsin-binding ligands, compositions and methods of use | BIKAM PHARMACEUTICALS, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20140256782-A1 | Opsin-Binding Ligands, Compositions and Methods of Use | BIKAM PHARMACEUTICALS, INC. (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137398-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | CRYAB, CRYAA, PDE6C | CYP19A1 4114/4885SOD1 3456/4885CYP3A4 4427/4885 |
| US-20140256782-A1 | Opsin-Binding Ligands, Compositions and Methods of Use | CRYAB, PDE6C, CRYAA | CYP19A1 3985/4885SOD1 3310/4885CYP3A4 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.