Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.51 |
| ▸ | FDPS | P14324 | 11/20 | 0.48 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Taxodione SCHEMBL3847860 | 0.68 | EP300 (1.00) | EP300FDPSGGPS1CACNA1GCYP3A4 | |
| Taxodione SCHEMBL23630260 | 0.68 | EP300 (1.00) | EP300FDPSGGPS1CACNA1GCYP3A4 | |
| SCHEMBL18290373 | 0.67 | EP300 (0.66) | EP300FDPSGGPS1CYP3A4TP53 | |
| SCHEMBL18290366 | 0.67 | EP300 (0.66) | EP300FDPSGGPS1CACNA1GCYP3A4 | |
| SCHEMBL29929294 | 0.67 | EP300 (0.66) | EP300FDPSGGPS1CYP3A4TP53 | |
| SCHEMBL15732245 | 0.65 | EP300 (0.46) | EP300FDPSGGPS1CACNA1GHIF1A | |
| SCHEMBL8855191 | 0.61 | KARS1 (0.53) | CYP3A4TP53MAPTALDH1A1ALOX15 | |
| SCHEMBL8855131 | 0.61 | KARS1 (0.51) | EP300CYP3A4TP53MAPTALDH1A1 | |
| SCHEMBL22861880 | 0.59 | EP300 (0.64) | EP300FDPSGGPS1CYP3A4TP53 | |
| SCHEMBL29574656 | 0.58 | FDPS (0.50) | EP300FDPSGGPS1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016192631-A1 | ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME | 中国科学院上海药物研究所 | 2016-12-08 | — | — | WO | disclosed |