Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1416383 | 0.97 | CA12 (0.52) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL4622713 | 0.97 | CA12 (0.52) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL14763241 | 0.97 | CA12 (0.52) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL25230061 | 0.97 | CA12 (0.52) | CA12CA1CA9CA2ZDHHC20 | |
| Hydrochloric Acid SCHEMBL11600423 | 0.97 | CA12 (0.48) | CA12CA1CA9CA2MMP1 | |
| SCHEMBL25272614 | 0.97 | CA12 (0.52) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL78938 | 0.97 | CA12 (0.52) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL4623644 | 0.97 | CA12 (0.52) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL7652815 | 0.97 | CA12 (0.52) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL4623978 | 0.97 | CA12 (0.52) | CA12CA1CA9CA2ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7815724-B2 | Ink composition | FUJIFILM CORPORATION (JP) | 2010-10-19 | — | — | US | claimed |
| EP-0885239-B1 | NOVEL STEROID CARBAMATES AS POTENTIATING AGENTS | BATRA SATISH (SE) | 2002-08-07 | — | — | EP | claimed |
| EP-0677507-B1 | PROCESS FOR PRODUCING ACID-ADDITION SALT OF Z-ISOMER OF TRIPHENYLETHYLENE COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 1998-04-08 | — | — | EP | claimed |
| EP-0827953-A2 | Method for producing N-acyl carbamate | Nippon Paint Co., Ltd. (JP) | 1998-03-11 | — | — | EP | claimed |
| US-5565611-A | Process for preparing acid addition salt of Z-isomer of triphenylethylene compound | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-10-15 | — | — | US | claimed |
| EP-0677507-A1 | PROCESS FOR PRODUCING ACID-ADDITION SALT OF Z-ISOMER OF TRIPHENYLETHYLENE COMPOUND | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1995-10-18 | — | — | EP | claimed |
| US-4699905-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-13 | — | — | US | claimed |
| EP-4149920-B1 | PROCESS FOR THE SYNTHESIS OF ISOCYANATES | UNIV FREIBERG TECH BERGAKADEMIE (DE) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023106377-A1 | METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND | 旭化成株式会社 | 2023-06-15 | — | — | WO | disclosed |
| CN-109475574-A | Crosslinkable coating compositions formulated with dormant carbamate initiators | 海名斯精细化工公司 | 2019-03-15 | — | — | CN | disclosed |
| US-20180177760-A1 | COMPOSITIONS COMPRISING BIOREVERSIBLE DERIVATIVES OF HYDROXY N-SUBSTITUTED-2-AMINOTETRALINS, AND RELATED DOSAGE FORMS | SPRIASO LLC (US) | 2018-06-28 | — | — | US | disclosed |
| US-9956201-B2 | Compositions comprising bioreversible derivatives of hydroxy N-substituted-2-aminotetralins, and related dosage forms | SPRIASO LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160016887-A1 | Methods of treating a subject using bioreversible derivatives of hydroxy n-substituted-2-aminotetralins | SPRIASO LLC | 2016-01-21 | — | — | US | disclosed |
| US-4264625-A | INSECTICIDES, MITICIDES, NEMATOCIDES | UNION CARBIDE CORPORATION (US) | 1981-04-28 | — | — | US | disclosed |
| US-4239904-A | Process for the preparation of urethanes | ATLANTIC RICHFIELD COMPANY (US) | 1980-12-16 | — | — | US | disclosed |
| US-4181734-A | Pesticidal N-[2,2-dimethyl-2,3-dihydro-7-benzofuranyl-methyl-carbamate]N-[4-] sulfide | UNION CARBIDE CORPORATION (US) | 1980-01-01 | — | — | US | disclosed |
| US-4166864-A | MITICIDES, INSECTICIDES | UNION CARBIDE CORPORATION (US) | 1979-09-04 | — | — | US | disclosed |
| US-4124721-A | NEMATOCIDES, INSECTICIDES, MITICIDES | UNION CARBIDE CORPORATION (US) | 1978-11-07 | — | — | US | disclosed |
| US-3997597-A | ANTIOXIDANTS FOR LUBRICANTS AND GREASES | MOBIL OIL CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
| US-3771979-A | LIQUID HYDROCARBON CONTAINING ALKALI METAL SALTS OF DIARYLCARBAMATES AS ANTIKNOCK AGENTS | HEIBA E | 1973-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016887-A1 | Methods of treating a subject using bioreversible derivatives of hydroxy n-substituted-2-aminotetralins | SLC7A1, CYP2D6, SLC19A1 | CA12 2603/4885CA1 2522/4885CA9 3201/4885 |
| US-20180177760-A1 | COMPOSITIONS COMPRISING BIOREVERSIBLE DERIVATIVES OF HYDROXY N-SUBSTITUTED-2-AMINOTETRALINS, AND RELATED DOSAGE FORMS | SLC7A1, CYP2D6, CYP3A7 | CA12 3345/4885CA1 3251/4885CA9 3602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.