Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831618 | 0.85 | BACE1 (0.39) | BACE1CTSD | |
| SCHEMBL1827904 | 0.81 | BACE1 (0.40) | BACE1CTSD | |
| SCHEMBL3241071 | 0.80 | BACE1 (0.39) | BACE1CTSD | |
| SCHEMBL1832026 | 0.79 | BACE1 (0.45) | BACE1CTSD | |
| SCHEMBL1828227 | 0.74 | BACE1 (0.40) | BACE1CTSD | |
| SCHEMBL1829335 | 0.72 | BACE1 (0.44) | BACE1CTSD | |
| SCHEMBL12246431 | 0.70 | BACE1 (0.50) | BACE1CTSD | |
| SCHEMBL1826421 | 0.69 | BACE1 (0.47) | BACE1CTSD | |
| SCHEMBL1823413 | 0.67 | BACE1 (0.45) | BACE1CTSD | |
| SCHEMBL1821336 | 0.66 | BACE1 (0.65) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324032-A2 | INHIBITORS OF BETA-SECRETASE | Vitae Pharmaceuticals, Inc. (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |