Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.72 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13234954 | 0.89 | LMNA (0.60) | SRD5A2NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL3232949 | 0.89 | SRD5A2 (0.90) | SRD5A2NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL402300 | 0.87 | SRD5A2 (0.87) | SRD5A2NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL3415530 | 0.84 | SRD5A2 (0.81) | SRD5A2NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL6654887 | 0.81 | SRD5A2 (0.77) | SRD5A2NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL8503299 | 0.81 | SRD5A2 (0.77) | SRD5A2NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL10784972 | 0.81 | SRD5A2 (0.77) | SRD5A2NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL8067849 | 0.81 | SRD5A2 (0.77) | SRD5A2NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL19700405 | 0.80 | NR4A1 (0.50) | SRD5A2NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL7539817 | 0.80 | SRD5A2 (0.73) | SRD5A2NR4A1NR4A2NR4A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017212059-A1 | SYNTHESIS OF PHOTOACTIVABLE CAGED CYCLOFEN-OH AND DERIVATIVES THEREOF | PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) | 2017-12-14 | — | — | WO | disclosed |
| WO-2016196342-A1 | TETRASUBSTITUTED ALKENE COMPOUNDS AND THEIR USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-12-08 | — | — | WO | disclosed |