Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.77 |
| ▸ | RXRA | P19793 | 1/20 | 0.71 |
| ▸ | RXRB | P28702 | 1/20 | 0.71 |
| ▸ | PTGES | O14684 | 1/20 | 0.71 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.68 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.68 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 2/20 | 0.65 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.64 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27704685 | 0.95 | RXRA (0.74) | SRD5A2RXRARXRBPTGESNR4A1 | |
| SCHEMBL3232949 | 0.92 | SRD5A2 (0.90) | SRD5A2PTGESNR4A1NR4A2NR4A3 | |
| SCHEMBL402300 | 0.90 | SRD5A2 (0.87) | SRD5A2PTGESNR4A1NR4A2NR4A3 | |
| SCHEMBL3415530 | 0.87 | SRD5A2 (0.81) | SRD5A2PTGESNR4A1NR4A2NR4A3 | |
| SCHEMBL228292 | 0.86 | LMNA (0.67) | RXRARXRBNR4A1NR4A2NR4A3 | |
| Formaldehyde SCHEMBL27728539 | 0.84 | RXRA (0.62) | RXRARXRBPTGESNR4A1NR4A2 | |
| Methyl Alcohol SCHEMBL27428217 | 0.84 | LMNA (0.66) | RXRARXRBPTGESNR4A1NR4A2 | |
| SCHEMBL4953 | 0.84 | LMNA (0.64) | RXRARXRBNR4A1NR4A2NR4A3 | |
| SCHEMBL10784972 | 0.84 | SRD5A2 (0.77) | SRD5A2NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL6654887 | 0.84 | SRD5A2 (0.77) | SRD5A2PTGESNR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121480-A | LOW SPEED PALLADIUM-CATALYZED COUPLING OF ARYL GRIGNARD REAGENT WITH BROMOBENZONITRILE | GREAT LAKES CHEMICAL KONSTANZ GMBH (DE) | 2000-09-19 | — | — | US | disclosed |
| EP-0883603-A1 | METHOD FOR PRODUCING UNSYMMETRICALLY SUBSTITUTED BIPHENYLS | Great Lakes Chemical Konstanz GmbH (DE) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997030970-A1 | METHOD FOR PRODUCING UNSYMMETRICALLY SUBSTITUTED BIPHENYLS | GREAT LAKES CHEMICAL KONSTANZ GMBH (DE) | 1997-08-28 | — | — | WO | disclosed |