Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20038272 | 0.82 | OGA (0.35) | SOS1OGA | |
| SCHEMBL20255385 | 0.80 | PANK3 (0.36) | SOS1OGA | |
| SCHEMBL20249355 | 0.80 | SOS1 (0.33) | SOS1 | |
| SCHEMBL20037729 | 0.80 | BPTF (0.35) | SOS1SMN1; SMN2 | |
| SCHEMBL18291652 | 0.72 | OGA (0.33) | OGANR1I2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL18291286 | 0.71 | TLR9 (0.35) | OGANR1I2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL18291295 | 0.71 | NR1I2 (0.46) | OGANR1I2 | |
| SCHEMBL18291300 | 0.71 | IKBKB (0.36) | OGAHTTSMN1; SMN2 | |
| SCHEMBL18291666 | 0.70 | CHRNB2 (0.37) | OGANR1I2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9195108 | 0.70 | PDE10A (0.44) | OGANR1I2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016194831-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | 帝人ファーマ株式会社 | 2016-12-08 | — | — | WO | disclosed |