Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
| ▸ | VEGFA | P15692 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24765850 | 0.85 | VEGFA (0.48) | CHRM2CHRM4CHRM1CHRM3VEGFA | |
| SCHEMBL25231850 | 0.84 | CHRM2 (0.45) | CHRM2CHRM4CHRM1CHRM3VEGFA | |
| SCHEMBL29132115 | 0.83 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3VEGFA | |
| SCHEMBL29132216 | 0.82 | NR1H2 (0.45) | CHRM2CHRM4CHRM1CHRM3VEGFA | |
| SCHEMBL465791 | 0.81 | CHRM2 (0.47) | CHRM2CHRM4CHRM1CHRM3TBK1 | |
| SCHEMBL29132142 | 0.80 | FNTA (0.49) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL18291489 | 0.80 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3TBK1 | |
| SCHEMBL1997213 | 0.79 | MEN1 (0.49) | CHRM2CHRM4CHRM1CHRM3TBK1 | |
| SCHEMBL30584532 | 0.79 | MEN1 (0.49) | CHRM2CHRM4CHRM1CHRM3TBK1 | |
| SCHEMBL20483969 | 0.78 | VEGFA (0.47) | CHRM2CHRM4CHRM1CHRM3TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016194831-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | 帝人ファーマ株式会社 | 2016-12-08 | — | — | WO | disclosed |