Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15093956 | 0.86 | VEGFA (0.47) | VEGFAEGLN1TLR8CHRM2CHRM4 | |
| SCHEMBL15252410 | 0.84 | KDM4E (0.47) | KDM4EMAPTGPR119 | |
| SCHEMBL15094076 | 0.80 | ATM (0.45) | VEGFAEGLN1CHRM2CHRM4CHRM1 | |
| SCHEMBL30418929 | 0.80 | MAP4K4 (0.51) | MAP4K4ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL21698657 | 0.80 | MAP4K4 (0.51) | MAP4K4ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL465791 | 0.80 | CHRM2 (0.47) | VEGFAEGLN1CHRM2CHRM4CHRM1 | |
| SCHEMBL4291723 | 0.80 | NR1H2 (0.50) | VEGFAEGLN1FGFR1TLR8CHRM2 | |
| SCHEMBL20150071 | 0.80 | MGLL (0.48) | VEGFAEGLN1FGFR1CHRM2CHRM4 | |
| SCHEMBL465696 | 0.79 | TBK1 (0.51) | TLR8CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL18291473 | 0.78 | CHRM2 (0.46) | VEGFAEGLN1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696678-B2 | Kinase inhibitor, and preparing method and pharmaceutical use thereof | GAN & LEE PHARMACEUTICALS (CN) | 2020-06-30 | — | — | US | disclosed |
| US-20180305363-A1 | KINASE INHIBITOR, AND PREPARING METHOD AND PHARMACEUTICAL USE THEREOF | GAN&LEE PHARMACEUTICALS (CN) | 2018-10-25 | — | — | US | disclosed |
| EP-3369734-A1 | KINASE INHIBITOR, AND PREPARING METHOD AND PHARMACEUTICAL USE THEREOF | Gan & Lee Pharmaceuticals (CN) | 2018-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696678-B2 | Kinase inhibitor, and preparing method and pharmaceutical use thereof | CDK1, MAP3K1, CSNK1A1 | VEGFA 3785/4885EGLN1 4838/4885FGFR1 138/4885 |
| US-20180305363-A1 | KINASE INHIBITOR, AND PREPARING METHOD AND PHARMACEUTICAL USE THEREOF | CDK1, MAP3K1, CSNK1A1 | VEGFA 3785/4885EGLN1 4838/4885FGFR1 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.