Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25231850 | 0.88 | CHRM2 (0.45) | ALDH1A1GPR119CHRM2CHRM4CHRM1 | |
| SCHEMBL22166944 | 0.83 | ACHE (0.48) | NR1H2ALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL18291473 | 0.82 | CHRM2 (0.46) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL24765850 | 0.82 | VEGFA (0.48) | ALDH1A1GPR119CHRM2CHRM4CHRM1 | |
| SCHEMBL29132115 | 0.80 | CHRM2 (0.44) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL30893463 | 0.80 | GPR119 (0.52) | NR1H2ALDH1A1GPR119MAPTLMNA | |
| SCHEMBL23960996 | 0.80 | GPR119 (0.52) | NR1H2ALDH1A1GPR119MAPTLMNA | |
| SCHEMBL22166943 | 0.79 | VEGFA (0.44) | NR1H2ALDH1A1VEGFAEGLN1STS | |
| SCHEMBL17481790 | 0.79 | ACKR3 (0.42) | NR1H2ALDH1A1GPR119CHRM2CHRM4 | |
| SCHEMBL27169461 | 0.78 | SCD (0.45) | ALDH1A1GPR119MAPTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |