SCHEMBL1829150

SCHEMBL1829150

CCN(CC)CC/C=C/c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
SIGMAR1 Q99720 3/20 0.46
BCHE P06276 3/20 0.43
ACHE P22303 3/20 0.43
NPC1 O15118 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HTR2A P28223 3/20 0.43
KCNH2 Q12809 1/20 0.41
IDO1 P14902 1/20 0.41
PAM P19021 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL372984 1.00 MEN1 (0.49) MEN1KMT2ASIGMAR1BCHEACHE
SCHEMBL1829239 0.87 MEN1 (0.47) MEN1KMT2ASIGMAR1BCHEACHE
SCHEMBL1829240 0.87 MEN1 (0.47) MEN1KMT2ASIGMAR1BCHEACHE
SCHEMBL11496816 0.85 ACHE (0.43) MEN1KMT2ABCHEACHENPC1
SCHEMBL4595058 0.85 SIGMAR1 (0.46) MEN1KMT2ASIGMAR1NPC1L3MBTL1
SCHEMBL1830416 0.84 KCNH2 (0.49) MEN1KMT2ASIGMAR1BCHEACHE
SCHEMBL1830414 0.84 KCNH2 (0.49) MEN1KMT2ASIGMAR1BCHEACHE
SCHEMBL8919687 0.82 MEN1 (0.51) MEN1KMT2ASIGMAR1BCHEACHE
SCHEMBL2953634 0.81 KCNH2 (0.51) BCHEACHEKCNH2
SCHEMBL9779050 0.81 KCNH2 (0.51) BCHEACHEKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399594-B2 Blocked-isocyanate silicone resins DOW CORNING CORPORATION (US) 2013-03-19 US disclosed
EP-2102286-B1 BLOCKED ISOCYANATE SILICONE RESINS DOW CORNING (US) 2011-05-11 EP disclosed
US-20100093902-A1 Blocked-Isocyanate Silicone Resins DOW CORNING CORPORATION 2010-04-15 US disclosed
EP-2102286-A1 BLOCKED ISOCYANATE SILICONE RESINS Dow Corning Corporation (US) 2009-09-23 EP disclosed
WO-2008088492-A1 BLOCKED ISOCYANATE SILICONE RESINS DOW CORNING CORPORATRION (US) 2008-07-24 WO disclosed
US-20070167587-A1 Process for producing polymer with functional end KURARAY CO., LTD. (JP) 2007-07-19 US disclosed
EP-1721912-A1 PROCESS FOR PRODUCING POLYMER WITH FUNCTIONAL END KURARAY CO., LTD. (JP) 2006-11-15 EP disclosed