Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | OXTR | P30559 | 3/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18291578 | 1.00 | POLB (0.50) | POLBTP53MAPTOXTRAVPR1A | |
| SCHEMBL20037784 | 0.87 | OXTR (0.48) | POLBTP53MAPTOXTRAVPR1A | |
| SCHEMBL18291743 | 0.87 | OXTR (0.48) | POLBTP53MAPTOXTRAVPR1A | |
| SCHEMBL20255419 | 0.87 | OXTR (0.48) | POLBTP53MAPTOXTRAVPR1A | |
| SCHEMBL18291731 | 0.87 | OXTR (0.48) | POLBTP53MAPTOXTRAVPR1A | |
| SCHEMBL20249136 | 0.85 | OXTR (0.46) | POLBTP53MAPTOXTRAVPR1A | |
| SCHEMBL20037690 | 0.85 | OXTR (0.46) | POLBTP53MAPTOXTRAVPR1A | |
| SCHEMBL20249138 | 0.85 | OXTR (0.46) | POLBTP53MAPTOXTRAVPR1A | |
| SCHEMBL16059596 | 0.81 | NPC1 (0.59) | POLBTP53MAPTOXTRAVPR1A | |
| SCHEMBL18291553 | 0.79 | SMN1; SMN2 (0.47) | POLBTP53MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016194831-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | 帝人ファーマ株式会社 | 2016-12-08 | — | — | WO | disclosed |