Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | OXTR | P30559 | 4/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1337005 | 0.90 | NPC1 (0.59) | NPC1RAB9AGPR55MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1336911 | 0.88 | NPC1 (0.58) | NPC1RAB9AGPR55MEN1KMT2A | |
| SCHEMBL14276865 | 0.88 | NPC1 (0.50) | NPC1RAB9AGPR55MEN1KMT2A | |
| SCHEMBL18291578 | 0.81 | POLB (0.50) | MEN1KMT2AGAAOXTRAVPR1A | |
| SCHEMBL18291592 | 0.81 | POLB (0.50) | MEN1KMT2AGAAOXTRAVPR1A | |
| SCHEMBL20255419 | 0.80 | OXTR (0.48) | MEN1KMT2AGAAOXTRAVPR1A | |
| SCHEMBL18291743 | 0.80 | OXTR (0.48) | MEN1KMT2AGAAOXTRAVPR1A | |
| SCHEMBL18291731 | 0.80 | OXTR (0.48) | MEN1KMT2AGAAOXTRAVPR1A | |
| SCHEMBL20037784 | 0.80 | OXTR (0.48) | MEN1KMT2AGAAOXTRAVPR1A | |
| SCHEMBL20037690 | 0.78 | OXTR (0.46) | NPC1RAB9AMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968257-A1 | METHODS AND COMPOSITONS FOR IMPROVING COGNITIVE FUNCTION | The Johns Hopkins University (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014144546-A1 | METHODS AND COMPOSITONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-09-18 | — | — | WO | disclosed |