Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.52 |
| ▸ | FABP1 | P07148 | 1/20 | 0.50 |
| ▸ | FABP6 | P51161 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719048 | 0.96 | CYP2C19 (0.59) | CYP2C19CYP1A2HRH3CXCR4FABP1 | |
| SCHEMBL1344396 | 0.89 | CYP2C19 (0.62) | CYP2C19CYP1A2HRH3CXCR4FABP1 | |
| Hydrochloric Acid SCHEMBL8177967 | 0.87 | CYP2C19 (0.61) | CYP2C19CYP1A2HRH3CXCR4FABP1 | |
| SCHEMBL10861718 | 0.86 | CYP1A2 (0.66) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL9644591 | 0.84 | CYP1A2 (0.63) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL10858528 | 0.84 | CYP1A2 (0.63) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL2158846 | 0.83 | CYP2C19 (0.61) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL30496433 | 0.83 | CYP2C19 (0.61) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL3265804 | 0.82 | CYP1A2 (0.70) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL515358 | 0.81 | CYP2C19 (0.59) | CYP2C19CYP1A2CXCR4FABP1FABP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3294732-B1 | BENZIMIDAZOLE AND IMADAZOPYRIDINE CARBOXIMIDAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE | GILEAD SCIENCES INC (US) | 2019-09-25 | — | — | EP | disclosed |
| US-20160354468-A1 | (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS | YEDA RES & DEV (IL) | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160354468-A1 | (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS | PPOX, PPIB, PPIA | CYP2C19 3159/4885CYP1A2 4476/4885HRH3 4205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.