Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601311 | 0.78 | TSHR (0.50) | TSHRKIF11MAPK1 | |
| SCHEMBL7157506 | 0.78 | TSHR (0.52) | TSHRCYP1A2KCNN4ALDH1A1TAAR1 | |
| SCHEMBL6685341 | 0.76 | TSHR (0.50) | TSHRCYP1A2KCNN4ALDH1A1TAAR1 | |
| SCHEMBL8365376 | 0.76 | TSHR (0.50) | TSHRCYP1A2KCNN4ALDH1A1TAAR1 | |
| SCHEMBL6062610 | 0.76 | TAAR1 (0.52) | TSHRCYP1A2KCNN4ALDH1A1TAAR1 | |
| SCHEMBL7409166 | 0.76 | TSHR (0.50) | TSHRCYP1A2KCNN4ALDH1A1TAAR1 | |
| SCHEMBL7736698 | 0.76 | TSHR (0.50) | TSHRCYP1A2KCNN4ALDH1A1TAAR1 | |
| Methylene Chloride SCHEMBL28935108 | 0.74 | TSHR (0.82) | TSHRCYP1A2KCNN4ALDH1A1TAAR1 | |
| SCHEMBL11306527 | 0.74 | TSHR (0.48) | TSHRCYP1A2KCNN4ALDH1A1TAAR1 | |
| SCHEMBL8208883 | 0.74 | TSHR (0.48) | TSHRCYP1A2KCNN4ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318363-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | Nuevolution A/S (DK) | 2011-05-11 | — | — | EP | claimed |
| WO-2009152824-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | NUEVOLUTION A/S (DK) | 2009-12-23 | — | — | WO | claimed |
| US-4016214-A | Preparation of ethynylbenzenes | WILLIAM H. RORER, INC. (US) | 1977-04-05 | — | — | US | claimed |
| WO-2023160647-A1 | PHARMACEUTICAL COMPOSITION COMPRISING ANTI-CTLA4-ANTI-PD-1 BISPECIFIC ANTIBODY AND CHIAURANIB | 康方药业有限公司 | 2023-08-31 | — | — | WO | disclosed |
| CN-107921047-B | Novel use of arylquinoline derivatives as angiogenesis mimicry inhibitors | 台睿生物科技股份有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-108713457-A | A kind of implantation methods of the folding basal part of the ear and Rosa roxburghii Tratt interplanting | 六枝特区舰航种养殖场 | 2018-10-30 | — | — | CN | disclosed |
| CN-108575517-A | A kind of implantation methods for improving Rosa roxburghii Tratt mouthfeel and improving Rosa roxburghii Tratt yield | 六枝特区舰航种养殖场 | 2018-09-28 | — | — | CN | disclosed |
| CN-107417509-A | A kind of preparation method of phenylacetic acid compound | 上海康鹏科技有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-106928044-A | A kind of preparation method of fluoro phenylacetic acid | 上海康鹏科技有限公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-105541545-A | Synthesis method for medical intermediate o-chlorobromobenzene of chlorophenyl dichloroethane | CHENGDU ZHONGHENG HUATIE TECH CO LTD | 2016-05-04 | — | — | CN | disclosed |
| CN-105541545-A | Synthesis method for medical intermediate o-chlorobromobenzene of chlorophenyl dichloroethane | CHENGDU ZHONGHENG HUATIE TECH CO LTD | 2016-05-04 | — | — | CN | disclosed |
| EP-0441207-A2 | Heteroaryl alkenes, process for their preparation, intermediates and their use | BASF Aktiengesellschaft (DE) | 1991-08-14 | — | — | EP | disclosed |
| EP-0123187-B1 | PROCESS FOR THE PREPARATION OF FLUORINATED PHENYLACETIC-ACID ESTERS AND FLUORINATED TRICHLOROETHYL BENZENES | BAYER AG (DE) | 1988-04-20 | — | — | EP | disclosed |
| US-4483962-A | TERPOLYMER OF 2,8-DIHALO-1,3-BUTADIENE, MONOALKENYL AROMATIC ALKYL HALIDE, AND UNSATURATED ACID MONOMER | LORD CORPORATION (US) | 1984-11-20 | — | — | US | disclosed |
| EP-0123187-A2 | Process for the preparation of fluorinated phenylacetic-acid esters and fluorinated trichloroethyl benzenes | BAYER AG (DE) | 1984-10-31 | — | — | EP | disclosed |
| US-4178466-A | Process for preparing phenyl trichloro-ethanes | GENERAL ELECTRIC COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4016214-A | Preparation of ethynylbenzenes | WILLIAM H. RORER, INC. (US) | 1977-04-05 | — | — | US | disclosed |
| US-4016214-A | Preparation of ethynylbenzenes | WILLIAM H. RORER, INC. (US) | 1977-04-05 | — | — | US | disclosed |
| US-3952067-A | Ethynylbenzenes | WILLIAM H. RORER, INC. (US) | 1976-04-20 | — | — | US | disclosed |
| US-3952067-A | Ethynylbenzenes | WILLIAM H. RORER, INC. (US) | 1976-04-20 | — | — | US | disclosed |