Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 2/20 | 0.34 |
| ▸ | EDNRA | P25101 | 2/20 | 0.34 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10541651 | 0.88 | HDAC8 (0.40) | HDAC8TRPA1CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL29196075 | 0.83 | TRPA1 (0.41) | HDAC8TRPA1CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL28856302 | 0.79 | MAPT (0.41) | TRPA1CYP1A2CYP2A6ALDH1A1LMNA | |
| SCHEMBL1424371 | 0.78 | METAP2 (0.38) | HDAC8TRPA1ALDH1A1LMNAMAPK1 | |
| Bromide SCHEMBL20984475 | 0.78 | MAPT (0.40) | TRPA1CYP1A2CYP2A6ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL20984391 | 0.78 | MAPT (0.40) | TRPA1CYP1A2CYP2A6ALDH1A1LMNA | |
| SCHEMBL8082331 | 0.76 | TRPA1 (0.36) | HDAC8TRPA1CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL11851841 | 0.76 | TRPA1 (0.36) | HDAC8TRPA1CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL1696247 | 0.75 | CSNK2A1 (0.41) | HDAC8ALDH1A1LMNAMAPTKAT2B | |
| SCHEMBL20984115 | 0.73 | GAA (0.43) | TRPA1ALDH1A1LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318450-B1 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | HEXCEL COMPOSITES LTD (GB) | 2014-02-26 | — | — | EP | disclosed |
| US-8461275-B2 | Curing agents and process for their manufacture | Hexcal Composites Limited (GB) | 2013-06-11 | — | — | US | disclosed |
| US-20110130525-A1 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | Hexcel Corporation Ltd (GB) | 2011-06-02 | — | — | US | disclosed |
| EP-2318450-A2 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | Hexcel Composites Limited (GB) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010018392-A2 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | HEXCEL COMPOSITES LIMITED (GB) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130525-A1 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | ARCN1, PUF60, RCOR1 | HDAC8 2562/4885TRPA1 3122/4885CYP1A2 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.