SCHEMBL5653955

SCHEMBL5653955

O=C=NS(=O)(=O)c1ccc(S(=O)(=O)N=C=O)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 12/20 0.37
PRSS1 P07477 12/20 0.37
PRSS2 P07478 12/20 0.37
PRSS3 P35030 12/20 0.37
LMNA P02545 2/20 0.37
AGO2 Q9UKV8 1/20 0.37
MAPT P10636 2/20 0.33
CYP2C19 P33261 2/20 0.33
HTT P42858 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
GAA P10253 1/20 0.33
ALDH1A1 P00352 1/20 0.33
DDAH1 O94760 1/20 0.33
TTR P02766 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22302 0.89 F2 (0.52) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL5655146 0.89 F2 (0.52) F2PRSS1PRSS2PRSS3MAPT
SCHEMBL1124662 0.89 F2 (0.52) F2PRSS1PRSS2PRSS3PKM
SCHEMBL1125078 0.89 F2 (0.52) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL7211 0.87 HTR6 (0.46) LMNAMAPTHTTHPGDALDH1A1
SCHEMBL182964 0.87 CYP3A4 (0.47) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL5653139 0.87 CYP3A4 (0.47) LMNAMAPTCYP2C19HTTCYP1A2
SCHEMBL7824474 0.85 CA12 (0.50) PKMGAAALDH1A1
SCHEMBL28209363 0.85 F2 (0.48) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL7471475 0.85 CA1 (0.48) MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9586446-B2 Ballistic resilient run-flat tire, kit and method thereof ACCELLA POLYURETHANE SYSTEMS LLC (US) 2017-03-07 US claimed
US-20160361956-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ACCELLA POLYURETHANE SYSTEMS LLC 2016-12-15 US claimed
EP-2819855-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF Arnco, Inc. (US) 2015-01-07 EP claimed
WO-2013130113-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-09-06 WO claimed
US-20130220507-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-08-29 US claimed
US-20040209982-A1 Foams expanding in a fire INTUMEX GMBH (AT) 2004-10-21 US claimed
EP-1469059-A2 Expandable foams in case of fire INTUMEX GmbH (AT) 2004-10-20 EP claimed
US-9586446-B2 Ballistic resilient run-flat tire, kit and method thereof ACCELLA POLYURETHANE SYSTEMS LLC (US) 2017-03-07 US disclosed
US-20160361956-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ACCELLA POLYURETHANE SYSTEMS LLC 2016-12-15 US disclosed
EP-2819855-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF Arnco, Inc. (US) 2015-01-07 EP disclosed
US-8821663-B2 Ballistic resilient run-flat tire, kit and method thereof ARNCO (US) 2014-09-02 US disclosed
WO-2013130113-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-09-06 WO disclosed
US-20130220507-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-08-29 US disclosed
EP-0132675-B1 PREPARATIONS OF POLYISOCYNATE CONTAINING REVERSIBLY BLOCKED CATALYSTS, PROCESS FOR THEIR PRODUCTION, THEIR USE IN THE PRODUCTION OF POLYURETHANES, AND ADDITION PRODUCTS OF SULFONYLISOCYANATES ON CATALYSTS WITH A STRUCTURE OF CARBOXYLATES OF TIN II OR IV BAYER AG (DE) 1988-12-07 EP disclosed
EP-0232541-A2 Polyisocyanate compositions containing latent tin-catalysts, their use in the preparation of polyurethane resins and reaction products of sulfonyl isocyanates with selected tin compounds BAYER AG (DE) 1987-08-19 EP disclosed
US-4638795-A FOR MEDICAL AND VETERINARY USE; BASED ON POLYURETHANES BAYER AKTIENGESELLSCHAFT (DE) 1987-01-27 US disclosed
US-4614785-A TERTIARY PHOSPHINE OR PERALKYLATED PHOSPHORUS ACID TRIAMIDE CATALYST BAYER AKTIENGESELLSCHAFT (DE) 1986-09-30 US disclosed
EP-0173252-A2 Process for the preparation of oligomeric polyisocyanates and their use in the preparation of polyurethane plastics BAYER AG (DE) 1986-03-05 EP disclosed
EP-0172379-A1 Material for orthopaedic bandages BAYER AG (DE) 1986-02-26 EP disclosed
EP-0132675-A2 Preparations of polyisocynate containing reversibly blocked catalysts, process for their production, their use in the production of polyurethanes, and addition products of sulfonylisocyanates on catalysts with a structure of carboxylates of tin II or IV BAYER AG (DE) 1985-02-13 EP disclosed