SCHEMBL278353

SCHEMBL278353

O=C=Nc1ccc(S(=O)(=O)c2ccc(N=C=O)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.52
TSHR P16473 2/20 0.52
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
MAPK1 P28482 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
HTR6 P50406 2/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MPO P05164 1/20 0.42
CYP2C9 P11712 1/20 0.42
GAA P10253 1/20 0.42
TRPA1 O75762 1/20 0.41
PKM P14618 2/20 0.38
CYP1A2 P05177 1/20 0.38
EPHX2 P34913 1/20 0.38
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7180551 1.00 CYP3A4 (0.52) CYP3A4TSHRCA1CA2MAPK1
SCHEMBL19193390 0.90 GAA (0.61) CYP3A4TSHRCA1CA2TDP1
SCHEMBL4551023 0.88 HTT (0.47) CYP3A4TSHRCA1CA2MAPK1
SCHEMBL17577475 0.85 MAPK1 (0.42) CYP3A4TSHRCA1CA2MAPK1
SCHEMBL17576538 0.82 PKM (0.39) CYP3A4TSHRCA1CA2MAPK1
SCHEMBL10348147 0.82 CYP3A4 (0.48) CYP3A4TSHRCA1CA2MAPK1
SCHEMBL2278953 0.82 POLB (0.53) CYP3A4TSHRCA1CA2MAPK1
SCHEMBL242025 0.82 CA2 (0.68) CYP3A4TSHRCA1CA2TDP1
SCHEMBL165024 0.82 CYP3A4 (0.48) CYP3A4TSHRCA1CA2MAPK1
SCHEMBL31148855 0.82 CYP3A4 (0.48) CYP3A4TSHRCA1CA2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2007 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024083887-A1 FREE-RADICAL POLYMERISATION OF UV-CROSSLINKING SILANE ACRYLATES IN AN ISOCYANATE-CONTAINING POLYURETHANE MATRIX FOLLMANN GMBH & CO. KG (DE) 2024-04-25 WO claimed
EP-4326795-A1 POLYMERIZATION OF A SILANE-MODIFIED POLYMER, WHICH IS PRODUCED BY MEANS OF A RADICAL CHAIN POLYMERIZATION, IN A POLYOL OR IN A PREPOLYMER WITH TERMINAL ISOCYANATE GROUPS, AND USE THEREOF IN POLYURETHANE FORMULATIONS Follmann GmbH & Co. KG (DE) 2024-02-28 EP claimed
CN-104945592-B The preparation of the polymer modified asphalt (PMB) of the multiamide base amine derived from polyethylene terephthalate (PET) 印度石油有限公司 2019-01-11 CN claimed
EP-2924096-B1 PREPARATION OF POLYMER MODIFIED BITUMEN (PMB) FROM POLYETHYLENE TEREPHTHALATE (PET) DERIVED POLYAMIDO AMINE INDIAN OIL CORP LTD (IN) 2019-01-02 EP claimed
US-9528001-B2 Preparation of polymer modified bitumen (PMB) from polyethylene terephthalate (PET) derived polyamido amine INDIAN OIL CORPORATION LTD. (IN) 2016-12-27 US claimed
US-9402860-B2 Methods of inhibiting the growth of onychomycosis and urushiol-induced allergic contact dermatitis CHESSON LABORATORY ASSOCIATES, INC. (US) 2016-08-02 US claimed
US-20160095811-A1 METHODS OF TREATING AND/OR PREVENTING NAIL DISORDERS AND/OR IMPROVING THE APPEARANCE OF A NAIL NAIL GENESIS LLC 2016-04-07 US claimed
US-9259436-B2 Poly(urea-urethane) compositions useful as topical medicaments and methods of using the same CHESSON LABORATORY ASSOCIATES, INC. (US) 2016-02-16 US claimed
US-20150274974-A1 PREPARATION OF POLYMER MODIFIED BITUMEN (PMB) FROM POLYETHYLENE TEREPHTHALATE (PET) DERIVED POLYAMIDO AMINE INDIAN OIL CORPORATION LTD. (IN) 2015-10-01 US claimed
EP-2924096-A1 PREPARATION OF POLYMER MODIFIED BITUMEN (PMB) FROM POLYETHYLENE TEREPHTHALATE (PET) DERIVED POLYAMIDO AMINE INDIAN OIL CORPORATION Ltd. (IN) 2015-09-30 EP claimed
US-4849262-A Pigment printing pastes and dyeing liquors containing stable dispersions of finely divided solid polyisocyanates BASF AKTIENGESELLSCHAFT (DE) 1989-07-18 US claimed
US-4816509-A POLYETHERURETHANE COPOLYMERS ASAHI DENKA KOGYO K.K. (JP) 1989-03-28 US claimed
EP-0165620-B1 MODIFIED THERMOSETTING IMIDE RESINS The Boots Company PLC (GB) 1988-08-03 EP claimed
US-4618632-A POLYESTERURETHANES, ACRYLATE REACTIVE DILUENT WESTINGHOUSE ELECTRIC CORP. (US) 1986-10-21 US claimed
EP-0102722-B1 MODIFIED THERMOSETTING IMIDE RESINS The Boots Company PLC (GB) 1986-10-01 EP claimed
EP-0165620-A1 Modified thermosetting imide resins The Boots Company PLC (GB) 1985-12-27 EP claimed
US-4520145-A BISIMIDE, POLYISOCYANATE, AND UNSATURATED POLYESTER THE BOOTS COMPANY PLC (GB) 1985-05-28 US claimed
EP-0102722-A1 Modified thermosetting imide resins The Boots Company PLC (GB) 1984-03-14 EP claimed
WO-1984000552-A1 MODIFIED THERMOSETTING IMIDE RESINS BOOTS CO PLC (GB) 1984-02-16 WO claimed
US-4369302-A Curable resin composition comprising cyanate ester and polyisocyanate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-01-18 US claimed