SCHEMBL182972

SCHEMBL182972

CCCCCCCCC1(CCCCCCCC)COc2c[nH]cc2OC1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 4/20 0.35
S1PR1 P21453 1/20 0.33
CETP P11597 3/20 0.33
GAA P10253 1/20 0.33
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP9 P14780 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PTPN1 P18031 1/20 0.31
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31464896 0.81 PRKCA (0.32) PRKCAPTPN1
SCHEMBL4850421 0.81 PRKCA (0.32) PRKCAPTPN1
SCHEMBL2340404 0.81 PRKCA (0.32) PRKCAPTPN1
SCHEMBL14748861 0.74 KDM4E (0.30)
SCHEMBL13527938 0.74 PRKCA (0.37) PRKCA
SCHEMBL4857662 0.73
SCHEMBL11727987 0.72 TSHR (0.40) ALDH1A1
SCHEMBL182582 0.71 PRKCA (0.36) PRKCAPTPN1
SCHEMBL182999 0.70 ALDH1A1 (0.41) S1PR1ALDH1A1
SCHEMBL13080609 0.70 PRKCA (0.32) PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465962-B1 ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES UNIV FLORIDA (US) 2012-01-04 EP disclosed
EP-1436286-A4 FUMAGILLOL DERIVATIVES AND PREPARING METHOD THEREOF IDRTECH INC (KR) 2004-12-15 EP disclosed
US-6791738-B2 CONTROLLING COLOR, BRIGHTNESS AND ENVIRONMENTAL STABILITY; POLY- 3,4-ALKYLENEDIOXYHETEROCYCLES UNIVERSITY OF FLORIDA 2004-09-14 US disclosed
EP-1436286-A1 FUMAGILLOL DERIVATIVES AND PREPARING METHOD THEREOF Idrtech Inc. (KR) 2004-07-14 EP disclosed
US-20030174377-A1 Electrochromic polymers and polymer electrochromic devices UNIVERSITY OF FLORIDA 2003-09-18 US disclosed
WO-2003027104-A1 FUMAGILLOL DERIVATIVES AND PREPARING METHOD THEREOF IDRTECH INC. (KR) 2003-04-03 WO disclosed