Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 12/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 12/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.34 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.34 |
| ▸ | USP14 | P54578 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827197 | 0.69 | HCRTR1 (0.33) | HCRTR1HCRTR2MAP3K5USP14 | |
| SCHEMBL1829951 | 0.69 | PDE2A (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL1824268 | 0.69 | HCRTR1 (0.33) | HCRTR1HCRTR2MAP3K5USP14 | |
| SCHEMBL28105678 | 0.69 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL28173190 | 0.65 | KCNJ1 (0.37) | NOTUMHCRTR1HCRTR2MAP3K5TET2 | |
| SCHEMBL24920391 | 0.64 | NOTUM (0.42) | NOTUMHCRTR1HCRTR2MAP3K5 | |
| SCHEMBL28046546 | 0.64 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL29124580 | 0.63 | ATR (0.38) | NOTUMHCRTR1HCRTR2 | |
| SCHEMBL1586336 | 0.63 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL24240280 | 0.62 | NOTUM (0.48) | NOTUMMAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104024226-B | Novel nicotinamide derivative or salt thereof | FUJIFILM CORP. (JP) | 2016-06-01 | — | — | CN | disclosed |