Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1004789 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28095057 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1004788 | 0.94 | — | — | |
| Bicarbonate SCHEMBL27593300 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28582066 | 0.94 | CA4 (0.67) | — | |
| Bicarbonate SCHEMBL25 | 0.94 | — | — | |
| Bicarbonate SCHEMBL29061109 | 0.94 | CA4 (0.67) | — | |
| Bicarbonate SCHEMBL2121875 | 0.94 | CA4 (0.67) | — | |
| Bicarbonate SCHEMBL1331273 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1331459 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115246832-A | Deubiquitinase USP25 and USP28 targeted inhibitors and preparation and application thereof | 深圳湾实验室 | 2022-10-28 | — | — | CN | disclosed |
| CN-109906221-B | N-alkylsulfonylindoline compound, agricultural and horticultural insecticide containing the same, and method of using the same | 日本农药株式会社 | 2021-10-01 | — | — | CN | disclosed |
| CN-105873911-B | Thiazolium compounds and its Pesticidal purposes | 住友化学株式会社 | 2018-07-24 | — | — | CN | disclosed |
| US-20160355475-A1 | NOVEL INDOLE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2016-12-08 | — | — | US | disclosed |
| EP-3089977-A1 | NOVEL INDOLE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2016-11-09 | — | — | EP | disclosed |
| CN-104334552-B | Fused heterocyclic compound | 住友化学株式会社 | 2016-08-31 | — | — | CN | disclosed |
| CN-105873911-A | Thiazole compounds and pest control applications thereof | 住友化学株式会社 | 2016-08-17 | — | — | CN | disclosed |
| WO-2015102426-A1 | NOVEL INDOLE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2015-07-09 | — | — | WO | disclosed |
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| EP-2318374-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010012442-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-02-04 | — | — | WO | disclosed |