Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 4/20 | 0.56 |
| ▸ | ATP4B | P51164 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5831979 | 0.83 | MIF (0.56) | TDP1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL12545668 | 0.82 | RAB9A (0.59) | SMN1; SMN2KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL12545473 | 0.82 | RAB9A (0.60) | TDP1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL5832578 | 0.81 | POLB (0.47) | ATP4AATP4BPOLBAPEX1HTT | |
| SCHEMBL19229535 | 0.81 | ATP4A (0.78) | ATP4AATP4BSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL5946741 | 0.81 | ATP4A (0.78) | ATP4AATP4BSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL5831358 | 0.81 | ATP4A (0.78) | ATP4AATP4BSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL29316005 | 0.79 | POLB (0.72) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL15462904 | 0.79 | ATP4A (0.83) | ATP4AATP4BTDP1SMN1; SMN2KDM4E | |
| SCHEMBL29316003 | 0.79 | POLB (0.72) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307798-B2 | ALIGNMENT COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2024-06-05 | — | — | EP | disclosed |
| CN-107743594-B | Alignment polymers | 光学转变公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-107743485-B | Alignment compound | 光学转变公司 | 2021-10-22 | — | — | CN | disclosed |
| EP-3307797-B1 | ALIGNMENT POLYMERS | TRANSITIONS OPTICAL INC (US) | 2021-10-20 | — | — | EP | disclosed |
| EP-3307797-B1 | ALIGNMENT POLYMERS | TRANSITIONS OPTICAL INC (US) | 2021-10-20 | — | — | EP | disclosed |
| US-11130912-B2 | Alignment polymers | TRANSITIONS OPTICAL, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-11130912-B2 | Alignment polymers | TRANSITIONS OPTICAL, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-10875833-B2 | Alignment compounds | TRANSITIONS OPTICAL, INC. (US) | 2020-12-29 | — | — | US | disclosed |
| US-10875833-B2 | Alignment compounds | TRANSITIONS OPTICAL, INC. (US) | 2020-12-29 | — | — | US | disclosed |
| EP-3307798-B1 | ALIGNMENT COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2020-08-05 | — | — | EP | disclosed |
| US-20180127653-A1 | Alignment Polymers | TRANSITIONS OPTICAL, INC. | 2018-05-10 | — | — | US | disclosed |
| EP-3307797-A1 | ALIGNMENT POLYMERS | Transitions Optical, Inc. (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-3307798-A1 | ALIGNMENT COMPOUNDS | Transitions Optical, Inc. (US) | 2018-04-18 | — | — | EP | disclosed |
| US-20180086725-A1 | Alignment Compounds | TRANSITIONS OPTICAL, INC. | 2018-03-29 | — | — | US | disclosed |
| US-20180086725-A1 | Alignment Compounds | TRANSITIONS OPTICAL, INC. | 2018-03-29 | — | — | US | disclosed |
| US-20180086725-A1 | Alignment Compounds | TRANSITIONS OPTICAL, INC. | 2018-03-29 | — | — | US | disclosed |
| WO-2016200401-A1 | ALIGNMENT COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2016-12-15 | — | — | WO | disclosed |
| WO-2016200401-A1 | ALIGNMENT COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2016-12-15 | — | — | WO | disclosed |
| WO-2016200394-A1 | ALIGNMENT POLYMERS | TRANSITIONS OPTICAL, INC. (US) | 2016-12-15 | — | — | WO | disclosed |
| WO-2016200394-A1 | ALIGNMENT POLYMERS | TRANSITIONS OPTICAL, INC. (US) | 2016-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10875833-B2 | Alignment compounds | CYP19A1, ESR1, CCNE2 | ATP4A 3905/4885ATP4B 3789/4885POLB 1750/4885 |
| US-20180086725-A1 | Alignment Compounds | CYP19A1, ESR1, CCNE2 | ATP4A 3905/4885ATP4B 3789/4885POLB 1750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.