SCHEMBL1830299

SCHEMBL1830299

COc1ccc(OC(=O)c2ccc(OCCCCC3CO3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.48
NPC1 O15118 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
MAPT P10636 5/20 0.46
KMT2A Q03164 5/20 0.45
PRSS1 P07477 2/20 0.45
ACR P10323 2/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
GFER P55789 1/20 0.44
PTPN2 P17706 1/20 0.43
PTPN1 P18031 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17307957 0.99 LMNA (0.49) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL8569019 0.94 LMNA (0.50) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL17431010 0.94 LMNA (0.50) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL17431006 0.92 LMNA (0.49) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL8574166 0.92 LMNA (0.51) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL17431005 0.91 LMNA (0.48) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL31556193 0.90 NPC1 (0.47) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL13703919 0.90 PRSS1 (0.48) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL9448805 0.89 LMNA (0.62) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL13882228 0.89 NPC1 (0.46) LMNANPC1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1813972-B1 Alignment Film NIPPON KAYAKU KK (JP) 2012-10-10 EP disclosed
CN-101016351-B Ultraviolet-curable urethane-(meth)acrylate polymer DEJIMA TECH BV 2012-07-04 CN disclosed
EP-1372004-B1 A PHASE DIFFERENCE FILM COMPRISING POLYMER FILM HAVING ULTRAVIOLET CURABLE RESIN COMPOSITION FOR ALIGNMENT FILM AND LIQUID CRYSTALLINE COMPOUND NIPPON KAYAKU KK (JP) 2011-05-11 EP disclosed
US-7445820-B2 Optical films comprising a UV-curable alignment film and a liquid crystal compound NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-11-04 US disclosed
US-7442420-B2 Retardation films comprising a UV-curable alignment film and a liquid crystal compound NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-10-28 US disclosed
CN-101016351-A Ultraviolet-curable urethane-(meth)acrylate polymer DEJIMA TECH BV (NL) 2007-08-15 CN disclosed
EP-1813972-A2 Alignment Film Nippon Kayaku Kabushiki Kaisha (JP) 2007-08-01 EP disclosed
EP-1767553-A1 UV-curable urethane-(meth)acrylate polymers Dejima Tech bv (NL) 2007-03-28 EP disclosed
EP-1767553-A1 UV-curable urethane-(meth)acrylate polymers Dejima Tech bv (NL) 2007-03-28 EP disclosed
US-20060008663-A1 Retardation films comprising a polymer film having a UV-curable resin composition for alignment film and a liquid crystalline compound TANAKA KOUICHI 2006-01-12 US disclosed
US-20050089650-A1 Phase difference film comprising polymer film having ultraviolet curable resin composition for alignment film and liquid crystalline compound NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2005-04-28 US disclosed
EP-1372004-A1 A PHASE DIFFERENCE FILM COMPRISING POLYMER FILM HAVING ULTRAVIOLET CURABLE RESIN COMPOSITION FOR ALIGNMENT FILM AND LIQUID CRYSTALLINE COMPOUND Nippon Kayaku Kabushiki Kaisha (JP) 2003-12-17 EP disclosed
EP-0868680-B1 TEMPERATURE MATCHED RETARDATION LAYER DEJIMA TECH BV (NL) 2001-05-23 EP disclosed
US-6088077-A Temperature matched retardation layer AKZO NOBEL NV (NL) 2000-07-11 US disclosed
EP-0868680-A1 TEMPERATURE MATCHED RETARDATION LAYER Akzo Nobel N.V. (NL) 1998-10-07 EP disclosed
WO-1997023805-A1 TEMPERATURE MATCHED RETARDATION LAYER AKZO NOBEL N.V. (NL) 1997-07-03 WO disclosed