Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
| ▸ | RELA | Q04206 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17431010 | 0.99 | LMNA (0.50) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL8569019 | 0.99 | LMNA (0.50) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL17431006 | 0.97 | LMNA (0.49) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL17431005 | 0.96 | LMNA (0.48) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL31556193 | 0.95 | NPC1 (0.47) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL13703919 | 0.94 | PRSS1 (0.48) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9448805 | 0.94 | LMNA (0.62) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL17307957 | 0.94 | LMNA (0.49) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL13882228 | 0.93 | NPC1 (0.46) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL1830299 | 0.92 | LMNA (0.48) | LMNANPC1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811504-A | CURABLE WITH CROSSLINKING AGENTS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1998-09-22 | — | — | US | disclosed |