Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699409 | 0.94 | PNMT (0.54) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL14975286 | 0.91 | PNMT (0.51) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL7699410 | 0.90 | PNMT (0.50) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL1830400 | 0.89 | PNMT (0.55) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL8671794 | 0.89 | PNMT (0.55) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL17456835 | 0.89 | PNMT (0.52) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL27921405 | 0.89 | PNMT (0.49) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL896998 | 0.88 | PNMT (0.54) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL8473288 | 0.88 | PNMT (0.54) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL8473291 | 0.88 | PNMT (0.54) | PNMTNPC1RAB9AHTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012131077-A1 | SOMATOSTATIN MIMETICS | NATIONAL UNIVERSITY OF IRELAND, GALWAY (IE) | 2012-10-04 | — | — | WO | claimed |
| EP-4370136-A2 | SIMPLE CHEMICAL APPROACHES TO INTRODUCE 2,6-DIAMINOPURINE AND 2-AMINOADENINE CONJUGATES INTO OLIGONUCLEOTIDES | Alnylam Pharmaceuticals, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023198857-A1 | \"GOOD\" BUFFER-BASED CATIONIC LIPIDS | SANOFI (FR) | 2023-10-19 | — | — | WO | disclosed |
| WO-2023196342-A1 | α4β1/7 INTEGRIN LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023178167-A1 | ASYMMETRIC PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2023096904-A2 | C-16 MODIFIED TRIOXACARCINS, ANTIBODY DRUG CONJUGATES, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-01 | — | — | WO | disclosed |
| EP-4164752-A1 | INHIBITORS OF TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAIN (TEAD) AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |
| EP-4161651-A1 | QUINAZOLINE-DERIVED HCK INHIBITORS FOR USE IN THE TREATMENT OF MYD88 MUTATED DISEASES | Dana-Farber Cancer Institute, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| WO-2023288045-A2 | SIMPLE CHEMICAL APPROACHES TO INTRODUCE 2,6-DIAMINOPURINE AND 2-AMINOADENINE CONJUGATES INTO OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| EP-4081202-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2022-11-02 | — | — | EP | disclosed |
| WO-2010011313-A2 | LIGATION OF STAPLED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-01-28 | — | — | WO | disclosed |
| WO-2010006343-A2 | GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2010-01-14 | — | — | WO | disclosed |
| WO-2008028057-A2 | SHIKIMIC ACID-DERIVED COMPOUNDS FOR INHIBITION AND DETECTION OF AURORA A-ASSOCIATED TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-03-06 | — | — | WO | disclosed |
| EP-1027070-A4 | CONJUGATE HEAT SHOCK PROTEIN-BINDING PEPTIDES | SLOAN KETTERING INSTITUTEFOR C (US) | 2004-08-18 | — | — | EP | disclosed |
| US-20030194409-A1 | Conjugate heat shock protein-binding peptides | ROTHMAN JAMES E (US) | 2003-10-16 | — | — | US | disclosed |
| US-20030166530-A1 | Conjugate heat shock protein-binding peptides | ROTHMAN JAMES E (US) | 2003-09-04 | — | — | US | disclosed |
| US-20030134787-A1 | Conjugate heat shock protein-binding peptides | ROTHMAN JAMES E (US) | 2003-07-17 | — | — | US | disclosed |
| EP-1027070-A1 | CONJUGATE HEAT SHOCK PROTEIN-BINDING PEPTIDES | Sloan-Kettering Institute For Cancer Research (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999022761-A9 | CONJUGATE HEAT SHOCK PROTEIN-BINDING PEPTIDES | SLOAN KETTERING INST CANCER (US) | 1999-08-12 | — | — | WO | disclosed |
| WO-1999022761-A1 | CONJUGATE HEAT SHOCK PROTEIN-BINDING PEPTIDES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1999-05-14 | — | — | WO | disclosed |