Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18304581 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRAKR1C3FBP1CA1 | |
| SCHEMBL60657 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL8557597 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| Benzene SCHEMBL27597826 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL6433811 | 0.74 | AKR1C3 (0.73) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL23458002 | 0.74 | AKR1C3 (0.73) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL598776 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| Ammonia Solution, Strong SCHEMBL28447731 | 0.72 | ALDH1A1 (0.56) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL11801120 | 0.72 | ALDH1A1 (0.56) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL27855636 | 0.72 | ALDH1A1 (0.56) | ALDH1A1TSHRAKR1C3FBP1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464861-B2 | Asymmetric addition reactions | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2019-11-05 | — | — | US | disclosed |
| EP-3307698-B1 | ASYMMETRIC ADDITION REACTIONS | UNIV OXFORD INNOVATION LTD (GB) | 2019-09-18 | — | — | EP | disclosed |
| US-20180334414-A1 | ASYMMETRIC ADDITION REACTIONS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2018-11-22 | — | — | US | disclosed |
| EP-3307698-A1 | ASYMMETRIC ADDITION REACTIONS | Oxford University Innovation Limited (GB) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016198836-A1 | ASYMMETRIC ADDITION REACTIONS | ISIS INNOVATION LIMITED (GB) | 2016-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464861-B2 | Asymmetric addition reactions | CSPP1, CCRL2, CBR3 | ALDH1A1 1009/4885TSHR 4030/4885AKR1C3 731/4885 |
| US-20180334414-A1 | ASYMMETRIC ADDITION REACTIONS | CSPP1, CCRL2, CBR3 | ALDH1A1 1009/4885TSHR 4030/4885AKR1C3 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.