SCHEMBL18304653

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6318301	0.82	KCNH2 (0.55)	KCNH2ERN1KDM4EMAPTLTA4H
	SCHEMBL1726249	0.82	KCNH2 (0.55)	KCNH2ERN1KDM4EMAPTLTA4H
	SCHEMBL16596476	0.79	ERN1 (0.48)	KCNH2ERN1KDM4EMAPTLTA4H
	SCHEMBL6300223	0.78	KCNH2 (0.50)	KCNH2ERN1MAPTLTA4HPGR
	SCHEMBL1133644	0.78	KCNH2 (0.50)	KCNH2ERN1KDM4EMAPTLTA4H
	SCHEMBL21999632	0.78	KCNH2 (0.70)	KCNH2ERN1KDM4EMAPTLTA4H
	SCHEMBL935142	0.76	LTA4H (0.57)	KCNH2ERN1KDM4EMAPTLTA4H
	SCHEMBL29945114	0.76	KCNH2 (0.52)	KCNH2ERN1KDM4EMAPTLTA4H
	SCHEMBL6744197	0.76	KCNH2 (0.52)	KCNH2ERN1KDM4EMAPTLTA4H
	SCHEMBL2368386	0.75	ERN1 (0.51)	KCNH2ERN1LTA4HPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.