SCHEMBL1830591

SCHEMBL1830591

CON1C(=O)CCCCC1c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.46
CHRNB2 P17787 1/20 0.44
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
CHRNA7 P36544 1/20 0.44
CHRNA4 P43681 1/20 0.44
HCRTR1 O43613 11/20 0.43
HCRTR2 O43614 11/20 0.43
ALDH1A1 P00352 1/20 0.41
SRD5A1 P18405 1/20 0.40
RIPK1 Q13546 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1827356 0.82 RIPK1 (0.45) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL8314501 0.79 KDM4E (0.53) SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL25017793 0.79 KDM4E (0.53) SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL27763838 0.78 RIPK1 (0.43) SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL23562447 0.75 CHRM2 (0.50) SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL25017792 0.75 SLC18A3 (0.46) SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL1240108 0.73 KDM4E (0.54) SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL11666714 0.72 SLC18A3 (0.56) SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL12918110 0.70 CHRNB2 (0.44) SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL9273128 0.70 CHRNB2 (0.53) SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1249812-A None JP disclosed
US-10072138-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD (JP) 2018-09-11 US disclosed
US-9567451-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-02-14 US disclosed
US-9493638-B2 Rubber composition for tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-11-15 US disclosed
US-9493629-B2 Modified butadiene-based polymer composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-11-15 US disclosed
US-9475924-B2 Rubber composition for tire tread and pneumatic tire using the same THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-10-25 US disclosed
US-9416252-B2 Rubber composition for tire tread THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-08-16 US disclosed
US-9139721-B2 Rubber composition for tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-09-22 US disclosed
US-20150126643-A1 Rubber Composition for Tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-05-07 US disclosed
US-20150031791-A1 Rubber Composition for Tire Treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-01-29 US disclosed
US-5217839-A Dispersion containing mixture of a polymer with a carbon nitrogen double bond and a colorant in a vinyl monomer NIPPON ZEON CO., LTD. (JP) 1993-06-08 US disclosed
US-5155161-A Living polymer modified by lactam, urea, amino ketone or aldehyde or thio analogs, followed by hydrolysis NIPPON ZEON CO., LTD. (JP) 1992-10-13 US disclosed
EP-0488346-A1 Process for preparation of styrene resin composition and styrene resin composition NIPPON ZEON CO., LTD. (JP) 1992-06-03 EP disclosed
EP-0438248-A2 Preparation process of toner NIPPON ZEON CO., LTD. (JP) 1991-07-24 EP disclosed
EP-0435544-A2 Abrasion-resistant rubber compositions NIPPON ZEON CO., LTD. (JP) 1991-07-03 EP disclosed
EP-0434353-A2 Rubber compositions NIPPON ZEON CO., LTD. (JP) 1991-06-26 EP disclosed
US-5001196-A Process for preparation of diene type polymer rubber NIPPON ZEON CO., LTD. (JP) 1991-03-19 US disclosed
EP-0388921-A2 Additive for organic solvent or thermoplastic polymer NIPPON ZEON CO., LTD. (JP) 1990-09-26 EP disclosed
EP-0382205-A2 Additive for thermosetting resins and thermosetting resin composition containing additive NIPPON ZEON CO., LTD. (JP) 1990-08-16 EP disclosed
JP-H01249812-A PRODUCTION OF DIENE-BASED POLYMER RUBBER AND RUBBER COMPOSITION THEREFROM NIPPON ZEON CO LTD 1989-10-05 JP disclosed