Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 1/20 | 0.32 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18306067 | 0.90 | P2RX7 (0.37) | ULK1ULK2MKNK2STK17AP2RX7 | |
| SCHEMBL20531898 | 0.89 | P2RX7 (0.36) | ULK1ULK2MKNK2STK17AP2RX7 | |
| SCHEMBL18313598 | 0.89 | P2RX7 (0.36) | ULK1ULK2MKNK2STK17AP2RX7 | |
| SCHEMBL18313617 | 0.89 | P2RX7 (0.36) | ULK1ULK2MKNK2STK17AP2RX7 | |
| SCHEMBL18305984 | 0.89 | P2RX7 (0.35) | ULK1ULK2MKNK2STK17AP2RX7 | |
| SCHEMBL18306085 | 0.88 | KMT2A (0.39) | ULK1ULK2MKNK2STK17AJAK2 | |
| SCHEMBL18313197 | 0.85 | P2RX7 (0.37) | ULK1ULK2MKNK2STK17AP2RX7 | |
| SCHEMBL20531942 | 0.85 | P2RX7 (0.37) | ULK1ULK2MKNK2STK17AP2RX7 | |
| SCHEMBL18313424 | 0.85 | ULK1 (0.36) | ULK1ULK2MKNK2STK17AP2RX7 | |
| SCHEMBL19987097 | 0.85 | ULK1 (0.36) | ULK1ULK2MKNK2STK17AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307741-A1 | POSITIVE ALLOSTERIC MODULATORS OF MUSCARINIC M2 RECEPTOR | Bayer Pharma Aktiengesellschaft (DE) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016198342-A1 | POSITIVE ALLOSTERIC MODULATORS OF MUSCARINIC M2 RECEPTOR | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-15 | — | — | WO | disclosed |