Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 8/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417618 | 1.00 | KCNN4 (0.42) | KCNN4TRPV3TRPA1KIF11CYP2D6 | |
| SCHEMBL7417614 | 1.00 | KCNN4 (0.42) | KCNN4TRPV3TRPA1KIF11CYP2D6 | |
| SCHEMBL10053574 | 0.81 | KCNN4 (0.50) | KCNN4TRPA1KIF11CYP2D6ALDH1A1 | |
| SCHEMBL1776001 | 0.78 | RCE1 (0.39) | KCNN4TRPV3TRPA1CYP2D6CYP2C19 | |
| SCHEMBL3852207 | 0.77 | KCNN4 (0.47) | KCNN4TRPA1KIF11 | |
| SCHEMBL6565005 | 0.77 | KCNN4 (0.47) | KCNN4TRPA1KIF11 | |
| SCHEMBL3854524 | 0.77 | KCNN4 (0.47) | KCNN4TRPA1KIF11 | |
| SCHEMBL3853261 | 0.76 | KCNN4 (0.50) | KCNN4TRPA1KIF11CYP2D6ALDH1A1 | |
| SCHEMBL3666885 | 0.76 | KCNN4 (0.50) | KCNN4TRPA1KIF11CYP2D6ALDH1A1 | |
| SCHEMBL4484584 | 0.76 | KCNN4 (0.50) | KCNN4TRPA1KIF11CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160362445-A1 | SOLID PHASE PEPTIDE SYNTHESIS VIA SIDE CHAIN ATTACHMENT | CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) | 2016-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362445-A1 | SOLID PHASE PEPTIDE SYNTHESIS VIA SIDE CHAIN ATTACHMENT | HDGF, VIP, HDGFL3 | KCNN4 4849/4885TRPV3 4674/4885TRPA1 4751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.