Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BAX | Q07812 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208440 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2CHRM5CHRM3IDO1POLB | |
| SCHEMBL6921848 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2CHRM5CHRM3IDO1POLB | |
| SCHEMBL1993991 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2CHRM5CHRM3POLBCXCR4 | |
| SCHEMBL27349170 | 0.80 | TSHR (0.44) | SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2326262 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2CHRM5CHRM3POLBCXCR4 | |
| Ammonia Solution, Strong SCHEMBL1308109 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2CHRM5CHRM3IDO1POLB | |
| Hydrochloric Acid SCHEMBL6619286 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2CHRM5CHRM3POLBCXCR4 | |
| Hydrochloric Acid SCHEMBL7515490 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2CHRM5CHRM3POLBCXCR4 | |
| Hydrochloric Acid SCHEMBL7417896 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2CHRM5CHRM3POLBCXCR4 | |
| SCHEMBL14498527 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618977-A1 | LRRK2 INHIBITORS AND USES THEREOF | Neuron23, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| US-20240208972-A1 | LRRK2 INHIBITORS AND USES THEREOF | NEURON23, INC. | 2024-06-27 | — | — | US | disclosed |
| WO-2024108116-A1 | LRRK2 INHIBITORS AND USES THEREOF | NEURON23, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| US-20230066771-A1 | NUCLEAR RECEPTOR MODULATORS | ABBVIE INC (US) | 2023-03-02 | — | — | US | disclosed |
| US-20210130293-A1 | NUCLEAR RECEPTOR MODULATORS | ABBVIE INC (US) | 2021-05-06 | — | — | US | disclosed |
| EP-3636643-A1 | NUCLEAR RECEPTOR MODULATORS (ROR) FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES | AbbVie Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| US-20190055196-A1 | NUCLEAR RECEPTOR MODULATORS | ABBVIE INC (US) | 2019-02-21 | — | — | US | disclosed |
| CN-107820494-A | Nuclear receptor modulators | 艾伯维公司 | 2018-03-20 | — | — | CN | disclosed |
| WO-2017161344-A1 | COMPOSITIONS AND METHODS FOR TREATING PARASITIC DISEASES | THE REGANTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-09-21 | — | — | WO | disclosed |
| US-20160362370-A1 | NUCLEAR RECEPTOR MODULATORS | ABBVIE INC. (US) | 2016-12-15 | — | — | US | disclosed |
| WO-2016200851-A1 | NUCLEAR RECEPTOR MODULATORS | ABBVIE INC. (US) | 2016-12-15 | — | — | WO | disclosed |
| US-20160362370-A1 | NUCLEAR RECEPTOR MODULATORS | ABBVIE INC. (US) | 2016-12-15 | — | — | US | disclosed |
| WO-2016198908-A1 | ROR NUCLEAR RECEPTOR MODULATORS | ABBVIE INC. (US) | 2016-12-15 | — | — | WO | disclosed |
| CN-103313982-B | Phenyl-isoxazole derivatives and process for the preparation thereof | IL-YANG PHARM. CO.,LTD. (KR) | 2016-02-03 | — | — | CN | disclosed |
| CN-103313982-A | Phenyl-isoxazole derivatives and process for the preparation thereof | IL YANG PHARM CO LTD | 2013-09-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362370-A1 | NUCLEAR RECEPTOR MODULATORS | NR1I2, NR1H2, NR5A2 | SMN1; SMN2 4231/4885CHRM5 795/4885CHRM3 648/4885 |
| US-20210130293-A1 | NUCLEAR RECEPTOR MODULATORS | NR1I2, NR1H2, NR5A2 | SMN1; SMN2 4231/4885CHRM5 795/4885CHRM3 648/4885 |
| US-20240208972-A1 | LRRK2 INHIBITORS AND USES THEREOF | LRRK2, PINK1, PARK7 | SMN1; SMN2 778/4885CHRM5 4694/4885CHRM3 4715/4885 |
| US-20230066771-A1 | NUCLEAR RECEPTOR MODULATORS | NR1I2, NR1H2, NR5A2 | SMN1; SMN2 4231/4885CHRM5 795/4885CHRM3 648/4885 |
| US-20190055196-A1 | NUCLEAR RECEPTOR MODULATORS | NR1I2, NR1H2, NR5A2 | SMN1; SMN2 4231/4885CHRM5 795/4885CHRM3 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.